Author Archives: Karely Vega, MD

Trigonelline Derived from Coffee Improves Cognitive Functions in Mice

The search for functional natural compounds that can improve age-related cognitive decline has recently emerged as an important research focus to promote healthy aging. Trigonelline (TG), a plant alkaloid found in coffee, as well as in fenugreek seed and radish, was anticipated to possess cognitive enhancement properties. In this study, researchers led by the University […]

New Research Adds Evidence to the Benefits of Ginger Supplements for Treating Autoimmune Diseases

New research has revealed a potentially important role ginger supplements can play in controlling inflammation for people living with autoimmune diseases. The research published in JCI Insight focused on studying the impact of ginger supplementation on a type of white blood cell called the neutrophil. The study was especially interested in neutrophil extracellular trap (NET) […]

Embryonic Humanized Kidneys Inside Pigs

Guangzhou Institutes of Biomedicine and Health researchers have successfully created chimeric embryos containing a combination of human and pig cells. When transferred into surrogate pig mothers, the developing humanized kidneys had normal structure and tubule formation after 28 days.  The work appears in the journal Cell Stem Cell. The researchers focused on kidneys because they […]

Healthy Lifestyle Can Help Prevent Depression — and New Research May Explain Why

A healthy lifestyle that involves moderate alcohol consumption, a healthy diet, regular physical activity, healthy sleep and frequent social connection, while avoiding smoking and too much sedentary behaviour, reduces the risk of depression, new research has found. In research published today in Nature Mental Health, an international team of researchers, including from the University of […]

New Way to Target Cancer Cells

Researchers from the University of Arizona Cancer Center have identified a new method of activating specific molecules to target cancer cells while leaving healthy cells unharmed. In their recent study, published in the Journal of the American Chemical Society, Wei Wang, PhD, and his team developed a new strategy called click-release proteolysis targeting chimeras, or […]

Immune Cells in Old and Young

A world-first discovery has revealed special immune cells called ‘killer T cells’ in older adults, directed against influenza viruses, closely resemble those found in newborns and children, but struggle to recognise infected cells — a finding that unlocks the potential for the development of better vaccines and therapies tailored to different age groups. Killer T […]

Injection-Free Control of Diabetes

One promising approach to treating Type 1 diabetes is implanting pancreatic islet cells that can produce insulin when needed, which can free patients from giving themselves frequent insulin injections. However, one major obstacle to this approach is that once the cells are implanted, they eventually run out of oxygen and stop producing insulin. To overcome […]

Phthalates and Brain Development

Children whose mothers had a higher exposure to certain phthalates during pregnancy tend to show smaller total gray matter in their brains at age 10. This is one of the main conclusions of a study led by the NYU Grossman School of Medicine and the Barcelona Institute for Global Health (ISGlobal), a centre supported by […]

Genetic Biomarker May Predict Severity of Food Allergy

Researchers from Ann & Robert H. Lurie Children’s Hospital of Chicago and colleagues reported for the first time that a genetic biomarker may be able to help predict the severity of food allergy reactions.  Currently there is no reliable or readily available clinical biomarker that accurately distinguishes patients with food allergies who are at risk […]

Strengthening Artificial Immune Cells to Fight Cancer

Among available immunotherapies, the use of “CAR-T” cells is proving extremely effective against certain blood cancers, but only in half of patients. A main reason for this is the premature dysfunction of these immune cells, which have been artificially modified in vitro. A team from the Universities of Geneva (UNIGE), Lausanne (UNIL), the Geneva University […]