Fish Skin has Anti-Aging Properties That Prevent Wrinkles

Pacific whiting is caught in large volumes in the United States but consumers have little familiarity with the mild, white meat fish also known as hake.

The gelatin in the skin of Pacific whiting, an abundant fish on the Pacific Coast of North America, may help prevent skin wrinkling caused by ultraviolet radiation, a new Oregon State University study found.

In a paper recently published in the journal Marine Drugs, Kwon and a team of researchers looked at molecular pathways that contribute on a cellular level to the wrinkling of skin. That wrinkling is promoted by chronic exposure to ultraviolet light, which breaks down collagen in the skin.

The researchers extracted gelatin from Pacific whiting fish and then looked at what impact it had on anti-oxidant and inflammatory responses and pathways known to degrade collagen and promote synthesis of collagen.

They found that the Pacific whiting skin:

  • Reactivated to a certain level the collagen synthesis pathway that had been suppressed by UV radiation.
  • Prevented activation to a certain level of the collagen degradation pathway that had been accelerated by UV radiation.
  • Promoted additional anti-oxidant activity. Antioxidants are substances that can prevent or slow damage to cells.
  • Promoted additional anti-inflammatory effects.

This is just the initial results of a study that promises skin fish to prevent the aging of human skin, preventing wrinkles, nevos, and many types of lesions that the UV radiation from the sun can make. Is necessary to do more research and experiments on animal models to keep forward on this  novel preventive measure  for our largest organ.  For future applications this could be a novel anti-aging treatment too. 


Seok Hee Han, Elaine Ballinger, Se-Young Choung, Jung Yeon Kwon. Anti-Photoaging Effect of Hydrolysates from Pacific Whiting Skin via MAPK/AP-1, NF-κB, TGF-β/Smad, and Nrf-2/HO-1 Signaling Pathway in UVB-Induced Human Dermal Fibroblasts. Sicence Daily. 

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