Addiction is defined as a chronic disease with the obligation to take drugs or alcohol, no control over restraining intake, and having negative emotional feelings during the withdrawal period. Addiction doesn’t just affect the addict’s life, but also it has a huge burden on the society and economy. It has been revealed that addictive agents […]
What is Henoch-Schonlein Purpura? Henoch-Schonlein purpura (HSP) is a systemic vasculitis caused by vascular allergic inflammation, and predominantly affects children. The disorder causes the small blood vessels in your skin, joints, intestines, and kidneys to become inflamed and bleed. The most striking feature of this form of vasculitis is a purplish rash, typically on the […]
Systemic lupus erythematosus (SLE) is a diffuse connective tissue disease that often affects multiple organs and systems, such as the kidneys, blood system, and nervous system. The disease is more common in women, and patients that have the condition need to take long-term glucocorticoids and immunosuppressants such as cyclophosphamide, mycophenolate mofetil, and other drugs in […]
Strokes are the third most common cause of death in adults in the world, and an important cause of mortality and chronic neurological morbidity in children. Arterial ischemic stroke has emerged as an important cause of neurological disability in children. The reported annual incidence ranges from 1.2 to 8 per 100,000 children and 1 per […]
Wounds to the skin are caused by mechanical, thermal, and chemical trauma. Scars are the normal outcome of wound repair and involve a coordinated inflammatory and fibrotic process. The scars normally remodel and become soft, flat, pale, and unobtrusive. However, in some cases, scars do not resolve and chronic inflammation can cause excessive scarring that […]
What is Premature Ovarian Insufficiency? Premature ovarian insufficiency (POI) is a type of ovarian dysfunction characterized by menstrual disorder, ovarian atrophy, decreased sexual life, and decreased fertility in women between puberty and 40 years of age. Is a condition that can seriously affect female reproductive health and endocrine balance, and is one of the main […]
Asthma is a chronic inflammatory disease of the airways caused by endogenous (such as chronic inflammation and oxidative stress) and exogenous factors (such as exposure to CS and air pollution), involving multiple cells and cellular components. In this condition, effector cells secrete inflammatory factors that cause inflammation, mediate peripheral tissue destruction, induce high secretion of […]
Psoriasis is a skin disease that causes a rash with itchy, scaly patches, most commonly on the knees, elbows, trunk, and scalp. Psoriasis is a common, long-term (chronic) disease with no cure. It can be painful, interfere with sleep, and make it hard to concentrate. The condition tends to go through cycles, flaring for a […]
What is Systemic Sclerosis? Systemic sclerosis (SSc) is an autoimmune disease marked by immunological deregulation, vasculopathy, and fibrosis of the skin and internal organs. Fibroblasts are the primary cells implicated with fibrosis: a process that involves increased production of extracellular matrix components (ECMs), such as collagen, and modifies connective tissue structure. Using Stem Cell Therapy […]
Only some organs have intrinsic repair and regenerative capacity in the human body, and different organs often show different rates of repair and regeneration, such as the peripheral nervous system. Sciatic nerve injury is a common peripheral neuropathy usually caused by trauma, indicating the loss of motor and sensory functions. Patients suffering from such injury […]