Monthly Archives: September 2023

Small Cell Lung Cancer: New Approach to Overcoming Chemo-Resistance

Small cell lung cancer accounts for about 15 percent of all diagnosed lung cancers and is still associated with a high mortality rate. SCLC tumours often develop resistance to chemotherapy and thus poor prognosis is due to tumour recurrence which occurs within only five to 14 months after initial diagnosis.  As a recent research study […]

A Dendritic Cell Vaccine Was Safe and Induced Immune Responses in Patients With Multiple Myeloma

ASCT is typically preceded by induction therapy with chemotherapy to kill as many cancer cells as possible and induce a remission. For this study, the investigators selected patients with high-risk disease who still had active myeloma after induction therapy and before receiving ASCT, which constitutes a negative prognostic factor. “We focused on this patient population […]

Malnutrition Early in Life Sets Stage for Poor Growth and Early Death

In 2022, more than one in five children around the world did not get enough calories to grow normally, and more than 45 million showed signs of wasting, or weighing too little for their height. More than a million children die each year as a consequence of wasting and more than 250,000 die from stunting. […]

Modeling Age-Related Macular Degeneration

Researchers at Utah State University have successfully demonstrated that hagfish slime proteins can accurately replicate membranes in the human eye. Professor Elizabeth Vargis and her team study a condition called age-related macular degeneration that causes damage to the retina, making it difficult to see. They study in vitro models, or a model developed in a […]

Increasing Steps by 3,000 Per Day Can Lower Blood Pressure in Older Adults, Study Finds

An estimated 80% of older adults in the U.S. have high blood pressure. Maintaining healthy blood pressure can protect against serious conditions like heart failure, heart attacks, and strokes. A new study found that adding a relatively minimal amount of movement, about 3,000 steps per day, can significantly reduce high blood pressure in older adults. […]

Brain Signals Linked to Good Memory Performance

People differ significantly in their memory performance. Researchers at the University of Basel have now discovered that certain brain signals are related to these differences. While it is well known that certain brain regions play a crucial role in memory processes, so far it has not been clear whether these regions exhibit different activities when […]

Cold Weather May Pose Challenges to Treating High Blood Pressure

According to the American Heart Association’s 2023 Statistical Update, nearly half of adults in the U.S. have high blood pressure. Previous research found that blood pressure varies with the seasons of the year. Most of this variation is in systolic blood pressure — the top number in a blood pressure reading that gauges the pressure […]

Insights on a New Online AI-Based Test for Parkinson’s Disease SeverityBrain Signals Linked to Good Memory Performance

Doctors often have patients perform simple motor tasks to assess movement disorders and rate the severity using guidelines such as the Movement Disorder Society Unified Parkinson’s Disease Rating Scale (MDS-UPDRS). The AI model provides a rapid assessment using the MDS-UPDRS guidelines, automatically generating computational metrics such as speed, amplitude, frequency, and period that are interpretable, […]

Trigonelline Derived from Coffee Improves Cognitive Functions in Mice

The search for functional natural compounds that can improve age-related cognitive decline has recently emerged as an important research focus to promote healthy aging. Trigonelline (TG), a plant alkaloid found in coffee, as well as in fenugreek seed and radish, was anticipated to possess cognitive enhancement properties. In this study, researchers led by the University […]

New Research Adds Evidence to the Benefits of Ginger Supplements for Treating Autoimmune Diseases

New research has revealed a potentially important role ginger supplements can play in controlling inflammation for people living with autoimmune diseases. The research published in JCI Insight focused on studying the impact of ginger supplementation on a type of white blood cell called the neutrophil. The study was especially interested in neutrophil extracellular trap (NET) […]