Monthly Archives: February 2022

Investigators Discovered Long-term Viability of Stem Cell Derived Retinal Implant

Non-neovascular age-related macular degeneration (NNAMD) is a major medical condition that affects millions of people in the Western world. The use of Macular translocation surgery, transplantation of autologous adult retinal pigmental epithelial (RPE) cells, and injection of suspensions of human embryonic stem cell (hESC)-derived RPE cells have been pursued as potential treatments.  Recently, a team […]

Use of Umbilical Cord MSCs in Type 2 Diabetes

Diabetes mellitus (DM) is a metabolic disease in which hyperglycemia is observed in patients over long periods of time. It is generally classified into four major forms: gestational diabetes, maturity-onset diabetes of the young (MODY-1), type 1 diabetes mellitus, and type 2 diabetes mellitus. Type 2 diabetes mellitus (T2DM) is the most predominant type of […]

Umbilical Cord Tissue Cryopreservation

Mesenchymal stem cells (MSCs) differentiate into different cell types and have immunomodulatory and paracrine effects. These cells can be obtained from different adult tissues, including umbilical cord, which is an excellent source of MSCs.  This tissue can be obtained during vaginal or cesarean delivery without any risk for neither the baby nor the mother.  There […]

Healthy Gut Microbiome Tied to Better Cognition

The communication between the gut bacteria and the neurologic function, referred to as the gut-brain axis is a novel area of research that has shown us it can regulate different aspects of our health, including brain health through immunologic, metabolic, and endocrine pathways.  Different studies have shown associations between the gut microbial measures and neurological […]

New and Effective Therapeutic Option for Glioblastoma

Glioblastoma is an aggressive type of cancer that can occur in the brain or spinal cord. Glioblastoma forms from cells called astrocytes that support nerve cells. This type of tumor can appear at any age, but it is more common in older adults. It is considered a terminal disease, as its life expectancy is less […]

First Female Patient Cured of HIV After Stem Cell Transplant

In 2007, Timothy Ray Brown became the first person ever whom doctors declared to be cured of HIV. Thirteen years later, in 2020 researchers from the United Kingdom confirmed the second case of a person cured from HIV. In both cases the patients had a diagnosis of leukemia and lymphoma respectively, that required a stem […]

High Fiber Intake Associated with Lower Risk of Dementia

Researchers from the University of Tsukuba in Japan had found that higher levels of dietary fiber, particularly soluble fiber, are associated with a lower risk of developing dementia. The study results were published in the journal Nutritional Neuroscience. Dietary fiber is a component that reaches the large intestine without being affected by digestive enzymes in […]

COVID-19 Can Cause Placental Destruction and Insufficiency

When a new virus emerges there is always the anxiety for those more vulnerable to infectious diseases, but perhaps this is even more true for pregnant women, who fear not only for their health but also for their unborn children.  Studies performed when the COVID-19 pandemic started found that although pregnant women in China could […]

A New Clinical Trial Showed No Benefit of Using Ivermectin Compared to Standard Care

In a new study published in the journal JAMA Internal Medicine, researchers compared the use of ivermectin vs standard care in reducing the risk of severe disease in patients with COVID-19.  The study was an open-label randomized clinical trial that included a total of 490 patients from 20 government hospitals and COVID-19 quarantine center in […]

Protein Complex Associated with Regulation of Cellular Apoptosis and Necrosis

Apoptosis and necroptosis are 2 cell death pathways with very different immune consequences. Apoptosis results in nuclear and cytoplasmic condensation, cell shrinkage, and small apoptotic body formation, without damaging plasma membrane integrity, which does not cause an immune response/inflammation.  On the other hand necroptosis is manifested by organelle and cell swelling and eventual cell membrane […]