Category Archives: Regenerative Medicine News and General Information

Lidocaine Against Refractory Migraine

Chronic migraine is less common than episodic migraine but is associated with a higher disease burden and cost. Some of these patients suffer from refractory migraines, which are persistent and debilitating headaches that are unresponsive to standard treatments.  To be diagnosed with chronic migraine according to the International Classification of Headache Disorders, third edition (ICHD-3), […]

A Promise of Zika Vaccine

The outbreak of Zika virus (ZIKV) in 2015 to 2016 attracted global attention due to the dire teratogenic effects caused by this mosquito-borne RNA virus, including microcephaly and fetal mortality in infants born to infected mothers . As such, intense research efforts to develop effective therapies and prophylactic measures have pressed on, although to little […]

Hormone Therapy Has More Benefits than Risks

The reproductive years of a woman’s life are regulated by production of the hormones estrogen and progesterone by the ovaries. Estrogen regulates a woman’s monthly menstrual cycle and secondary sexual characteristics. In addition, it prepares the body for fertilization and reproduction. Progesterone concentrations rise in a cyclical fashion to prepare the uterus for possible pregnancy […]

New Way to Eradicate Bacterial Infection

Community-acquired pneumonia (CAP) is one of the most common infectious diseases addressed by clinicians and is an important cause of mortality and morbidity worldwide. Typical bacterial pathogens that cause CAP include S pneumoniae, H influenzae, and M catarrhalis. Numerous other organisms can cause CAP in the appropriate clinical setting.  Furthermore, the so-called “atypical CAP” pathogens […]

Metabolic Syndrome Increase Mental Deterioration

Metabolic syndrome has been a worldwide problem for years, it is a multisystemic disease that includes high weight, high blood pressure, high fasting glucose, and is related with an insulin resistance and high risk to develop other conditions like Cardiovascular Disease. One of the possible causes of Dementia, mainly in the 70 year old population, […]

Is Rituximab an Effective Treatment Against Myasthenia?

Myasthenia gravis (MG) is a relatively rare autoimmune disorder in which antibodies form against nicotinic acetylcholine (ACh) postsynaptic receptors at the neuromuscular junction (NMJ) of the skeletal muscles, causing muscle weakness and rapid muscle fatigue. It is a type-II hypersensitivity immune response.  The basic pathology is a reduction in the number of ACh receptors (AChRs) […]

Prospective Treatment for Chronic Granulomatous Disease

Chronic granulomatous disease (CGD) is by mutations in genes coding for subunits or regulatory proteins of the NADPH oxidase complex, that is, X-linked mutations in CYBB or autosomal recessive mutations in CYBA, NCF1, NCF2, and CYBC1, that cause absent or severely reduced production of superoxide in all phagocytes , so they are unable to kill […]

New Gene Therapy Target for Polycystic Kidney Disease

Polycystic kidney disease is an inherited disease that involves bilateral renal cysts. The condition is broadly divided into 2 forms: autosomal dominant polycystic kidney disease (ADPKD) and autosomal recessive polycystic kidney disease (ARPKD). ADPKD is one of the most common inherited disorders in humans and the most frequent genetic cause of kidney failure in adults, […]

Second-Hand Smoke as a Risk Factor for Asthma not Only in Children, but Also in Grandchildren

Asthma is a common chronic disease worldwide and affects approximately 26 million persons in the United States. It is the most common chronic disease in childhood, affecting an estimated 7 million children, and it is a common cause of hospitalization for children in the United States. The pathophysiology of asthma is complex and involves airway […]

Is Acetaminophen Really a Safe Medication?

High blood pressure, or hypertension, is the most common primary diagnosis in the United States,  and it is one of the most common worldwide diseases afflicting humans and is a major risk factor for stroke, myocardial infarction, vascular disease, and chronic kidney disease. Despite extensive research over the past several decades, the etiology of most […]