Author Archives: Francisco Fernandez, MD

Healthy Gut Microbiome Tied to Better Cognition

The communication between the gut bacteria and the neurologic function, referred to as the gut-brain axis is a novel area of research that has shown us it can regulate different aspects of our health, including brain health through immunologic, metabolic, and endocrine pathways.  Different studies have shown associations between the gut microbial measures and neurological […]

New and Effective Therapeutic Option for Glioblastoma

Glioblastoma is an aggressive type of cancer that can occur in the brain or spinal cord. Glioblastoma forms from cells called astrocytes that support nerve cells. This type of tumor can appear at any age, but it is more common in older adults. It is considered a terminal disease, as its life expectancy is less […]

First Female Patient Cured of HIV After Stem Cell Transplant

In 2007, Timothy Ray Brown became the first person ever whom doctors declared to be cured of HIV. Thirteen years later, in 2020 researchers from the United Kingdom confirmed the second case of a person cured from HIV. In both cases the patients had a diagnosis of leukemia and lymphoma respectively, that required a stem […]

High Fiber Intake Associated with Lower Risk of Dementia

Researchers from the University of Tsukuba in Japan had found that higher levels of dietary fiber, particularly soluble fiber, are associated with a lower risk of developing dementia. The study results were published in the journal Nutritional Neuroscience. Dietary fiber is a component that reaches the large intestine without being affected by digestive enzymes in […]

COVID-19 Can Cause Placental Destruction and Insufficiency

When a new virus emerges there is always the anxiety for those more vulnerable to infectious diseases, but perhaps this is even more true for pregnant women, who fear not only for their health but also for their unborn children.  Studies performed when the COVID-19 pandemic started found that although pregnant women in China could […]

A New Clinical Trial Showed No Benefit of Using Ivermectin Compared to Standard Care

In a new study published in the journal JAMA Internal Medicine, researchers compared the use of ivermectin vs standard care in reducing the risk of severe disease in patients with COVID-19.  The study was an open-label randomized clinical trial that included a total of 490 patients from 20 government hospitals and COVID-19 quarantine center in […]

Protein Complex Associated with Regulation of Cellular Apoptosis and Necrosis

Apoptosis and necroptosis are 2 cell death pathways with very different immune consequences. Apoptosis results in nuclear and cytoplasmic condensation, cell shrinkage, and small apoptotic body formation, without damaging plasma membrane integrity, which does not cause an immune response/inflammation.  On the other hand necroptosis is manifested by organelle and cell swelling and eventual cell membrane […]

Study Identifies Genes Linked to Coronary Artery Disease

In a recently published study, researchers from the Victor Chang Cardiac Research Institute, the Icahn School of Medicine at New York’s Mount Sinai have identified the most critical genes that cause coronary heart disease and trigger heart attacks.  The researchers aimed to develop a comprehensive integrative genomics analysis for coronary artery disease (CAD) and provide […]

Study Found a New Way to Combat Leukemia Cells by Disrupting Their Energy Maintenance Mechanism

Acute myeloid leukemia (AML) is a myeloid-progenitor-derived neoplasm of poor prognosis, particularly among the elderly, in whom age and comorbidities preclude the use of intensive therapies. Around half the patients under the age of 60 die. For that reason there is an increased need for novel therapeutic approaches. Adenosine monophosphate (AMP)-activated protein kinase (AMPK) is […]

New Study Showed No Increased Risk of Infection With Cessation of Antibiotic Prophylaxis in Dentistry

Sweden is one of the few countries that have removed the dental health recommendation of giving prophylactic antibiotics in people at a higher risk of infection of the heart valves, an infection called infective endocarditis. The recommendation was removed in 2012, and since then there has been no increase in the disease.  What is Infective […]