A new study from researchers at Baylor College of Medicine and collaborating institutions reported in the journal Nature Cell Biology insights into the mechanism of how human NANOG facilitates the activation of cell pluripotency. Human NANOG expression resets stem cells to group-state pluripotency. In the study researchers identified unique features of human NANOG that relate […]
A good night’s sleep plays an important role in our health and cognitive function, it not only helps maintaining a good overall health, but it also helps in maintaining our psychological health. As we get older, we can start having alterations in our sleep patterns, which is thought to contribute to cognitive decline and psychiatric […]
Liver cancer is one of the top ten causes of cancer-related deaths worldwide and in the United States. Hepatocellular carcinoma (HCC) accounts for 75% of all liver cancer cases, most frequently occurring in patients with chronic liver diseases. The liver is also a frequent site for metastases originating from colorectal cancer, pancreatic cancer, melanoma, lung […]
In a new study, researchers from the School of Dental Medicine in collaboration with an international team that included colleagues at the Technical University of Dresden found a mechanism by which innate immune memory can cause one type of inflammation condition to increase susceptibility to another. For the study, the team used gum disease as […]
Pain is essential for our survival because it functions as a biological alarm for impeding or actual tissue damage. However, chronic pain is a persistent, inescapable stress, which leads to maladaptive emotional states. Studies have reported depression and anxiety-like behaviors in animal models of chronic pain, which suggest that it causes plastic changes in neural […]
Prostate cancer is the most common nonskin malignancy in men in developed countries, with over 250,000 deaths annually worldwide. Its clinical course can be highly heterogeneous, and critical decisions are made about the likelihood of aggressive disease based on information obtained at presentation, including histopathological scores. Genetic inheritance and ethnicity have established roles in prostate […]
A new and final recommendation has been issued by the U.S. Preventive Task Force on the use of aspirin in cardiovascular disease (CVD) prevention. “Evidence is pointing to the fact that we’re not seeing a benefit from using low-dose aspirin for reducing risk in patients who don’t already have cardiovascular disease,” says Dr. Demilade Adedinsewo, […]
Cellular reprogramming can manipulate the identity of cells to generate the desired cell types. The use of cell-intrinsic components, including oocyte cytoplasm and transcription factors, can enforce somatic cell reprogramming to pluripotent stem cells. By contrast, chemical stimulation by exposure to small molecules offers an alternative approach that can manipulate cell fate in a simple […]
A new study from Brown University and RIKEN Center for Brain Science has provided further evidence about the correlation between sleep and learning. There has always been a wrong belief that staying up late at night studying is the best and most normal way of learning, but according to the study, it may not be […]
Multiple sclerosis (MS) is a chronic condition that affects the central nervous system (CNS). It is characterized by the immune system attacking myelin sheaths, which are fatty layers that surround nerve fibers and enable them to communicate. One recent study published early this year found that contracting the Epstein-Barr virus (EBV), a type of herpesvirus, […]