Lifetime exposure to stressful conditions is a known risk factor for poorer health, increasing the risk for early onset of age-related disease and premature death. Models had examined the driving effects centering on the sequelae of repeated and prolonged activation of the sympathoadrenal and hypothalamic-pituitary-adrenal systems. Age is a robust determinant of immune cell population […]
Major depressive disorder (MDD) is one of the most prevalent and burdensome psychiatric disorders but current treatment options are still unsatisfying. Two-thirds of depressed patients do not respond adequately to initial antidepressant medication and up to 30% of treatment-resistant patients experience residual symptoms when receiving optimized treatments. That is why more efficient treatment approaches are […]
Alcohol consumption is one of the leading contributors to the global burden of disease and to high healthcare and economic costs. Alcohol use disorder (AUD) is one of the most prevalent mental health conditions worldwide, with harmful effects on physical, cognitive, and social functioning. Chronic excessive alcohol consumption is associated with direct and indirect adverse […]
Dementia is one of the major causes of disability and dependency among older people worldwide. This condition affects thinking and behaviors as you age. Is a chronic syndrome that leads to deterioration in cognitive function. Globally, more than 55 million people have dementia with 10 million new cases diagnosed every year. Recently, a group of […]
Coffee is one of the most often consumed beverages worldwide. It contains a wide variety of compounds, including caffeine, diterpenes, and cholinergic acid, which fully develop after the bean roasting process. These contents are reported to have different health benefits. The regular consumption of coffee has been associated in different studies to the prevention of […]
A new study presented at the Endocrine Society annual conference in Atlanta, GA, reports that two oral male contraceptive candidates were effective in suppressing hormones needed for sperm production and received a favorable response from most participants in the studies. The 2 drugs have properties that resemble androgens and are also similar to a lesser […]
Protein ingestion and physical activity stimulate muscle protein synthesis and are essential for the maintenance and accretion of skeletal muscle mass. The protein that is ingested during recovery from exercise further augments muscle protein synthesis rates and supports the skeletal muscle adaptive response to more prolonged exercise training. Habitually our protein intake originates from both […]
Excluding skin cancers, colorectal cancer is the third most common cancer diagnosed in the United States. The American Cancer Society’s estimates for the number of colorectal cancer cases in the United States for 2022 are 106.180 new cases of colon cancer and 44,850 new cases of rectal cancer. The rate of people being diagnosed with […]
For people with controlled type 2 diabetes mellitus (T2DM), the regulation of postprandial glycemia is essential to achieving optimal glycemic control, which may reduce the risk of complications associated with hyperglycemia. Other than medications, nutrition plays an integral and fundamental role in the management of T2DM and represents an opportunity to optimize glycemic control in […]
Sickle cell disease is an inherited blood disorder where red blood cells become sickle or crescent-shaped, which increases the risk of frequent infections, and is also characterized by painful recurrence of vaso-occlusive events that cause hands and legs swelling, pain, and severe tiredness with delayed growth or puberty. The standard medical treatment focuses on controlling […]