Sometimes kids trip and fall, and their teeth take the hit. Nearly half of children suffer some injury to a tooth during childhood. When that trauma affects an immature permanent tooth, it can hinder blood supply and root development, resulting in what is essentially a “dead” tooth. Until now, the standard of care has entailed […]
A genetic defect is the most common cause of hearing loss at birth and in childhood. These hearing losses have a profound negative impact on daily living. Numerous causative genes for genetic hearing loss have been identified. However, at present, there are no truly curative therapies for this condition. When considering curative treatments for genetic […]
People with serious food allergies face potentially fatal consequences if they’re accidentally exposed to triggering foods. But tests in allergic mice show that swallowing a form of butyrate, a compound produced by healthy gut bacteria, offers protection against peanut allergy, scientists report. The treatment might also counteract other food allergies, as well as inflammatory diseases. […]
A new study from University of Louisville researchers in the Christina Lee Brown Envirome Institute has found that exposure to e-cigarette aerosols can cause heart arrhythmias in animal models, both in the form of premature and skipped heart beats. The study findings, published Oct. 25 in Nature Communications, suggest exposure to specific chemicals within e-cigarette […]
Diabetes mellitus (DM) is a metabolic disease in which hyperglycemia is observed in patients over long periods of time. It is generally classified into four major forms: gestational diabetes, maturity-onset diabetes of the young (MODY-1), type 1 diabetes mellitus, and type 2 diabetes mellitus. Type 2 diabetes mellitus (T2DM) is the most predominant type of […]
Huntington’s disease (HD) is a neurological disorder that causes progressive loss of movement, coordination and cognitive function. It is caused by a mutation in a single gene called huntingtin or HTT. More than 200,000 people worldwide live with the genetic condition, approximately 30,000 in the United States. More than a quarter of a million Americans […]
Breaking bones can be life-changing events, especially as we age, when hip fractures can become particularly damaging and result in disability, compromised independence and a higher mortality risk. Research from Edith Cowan University’s Nutrition and Health Innovation Research Institute has revealed there may be something you can do to help reduce your risk of fractures […]
The increasing exploitation of nanomaterials including graphene-based materials necessitates a comprehensive evaluation of the potential effects of these materials on human health. However, although the interactions of nanomaterials with the immune system have been addressed, their impact on the microbiome of the host remains to be understood. Graphene is an extremely thin material, a million […]
Hematopoietic stem cells (HSCs) have the capacity to both self-renew and differentiate into all mature blood cell types, making them promising treatments for a variety of diseases. However, the mechanisms involved in engraftment — when the cells start to grow and make healthy blood cells after being transplanted into a patient — are poorly understood. […]
Researchers at UC San Francisco (UCSF) have engineered molecules that act like “cellular glue,” allowing them to direct in precise fashion how cells bond with each other. The discovery represents a major step toward building tissues and organs, a long-sought goal of regenerative medicine. Adhesive molecules are found naturally throughout the body, holding its tens […]