Animal studies have demonstrated that diets that severely restrict total calorie intake while providing all the essential nutrients can extend the average lifespan. Animal studies have revealed that the timing of calorie restriction can have an effect due to the circadian system, which controls daily cycles of physiology, metabolism, and behaviors such as eating. This […]
Older adults (aged 60 years) are the fastest-growing age group in the world and are projected to represent 1 in every 4 adults by 2050. Aging is associated with a progressive loss of muscle mass and strength that manifests as reduced physical performance and endurance capacity, imposing a burden on both the individual and society. […]
Despite the progress in medicine, the etiology of inflammatory bowel diseases (IBD), which are primarily Crohn’s disease (CD) and ulcerative colitis (UC), still remains unclear. What is more, the incidence of IBD, especially CD, is still increasing and the highest rates are found in the industrialized countries. It is believed that the disease process develops […]
Evidence indicates that a high-fat diet can promote gut inflammation and increase gut permeability. The use of antibiotics further exacerbates these complications and can lead to the development of inflammatory bowel disease. Inflammatory bowel disease (IBD) is an umbrella term used to describe disorders that involve chronic inflammation of your digestive tract. There are two […]
Male sub-fertility accounts for 50% of all causes of infertility in couples seeking in vitro fertilization (IVF) treatment, which can be due to low sperm count, aberrant sperm motility, or abnormal morphology. This problem is typically addressed using intracytoplasmic sperm injection (ICSI). ICSI is a slow and difficult procedure that involves the injection of a […]
Lifestyle and therapy interventions are considered the cornerstone for the management of obesity. Several guidelines recommend exercise, dietary, and behavioral interventions to improve weight loss in this population. Regarding exercise interventions, aerobic exercise (i.e., activity involving large muscle groups and performed in a continuous or intermittent fashion over an extended period of time, such as […]
Knee osteoarthritis (KOA) is a common condition affecting the adult population and resulting in a negative impact on quality of life. It is more prevalent in individuals older than 65 years. An estimated 9–14 million adults in the USA alone suffer from KOA. However, the prevalence is increasing among patients younger than 65 years. As […]
Prostate cancer screening using prostate-specific antigen (PSA) started around 1987 in the United States and has profoundly changed the epidemiology of prostate cancer, with a rapid doubling of incidence and, by 2015, a 50% decrease in annual prostate cancer mortality. There is still uncertainty regarding how much PSA screening is responsible for declining mortality rates […]
Rapid technological progress has shaped modern childhood. Time spent with digital devices has increased dramatically since the start of our twenty-first century and is now a large portion of a child’s free time. Children aged 8–12, for example, spend an average of 4–6 h with a screen each day watching videos, gaming and socializing. In […]
Antimicrobial resistance (AMR) represents a serious global health threat to humans and animals, with many reports predicting AMR as a major cause of death worldwide by 2050. Contributing to the growing epidemic are the overuse of antibiotics in farming practices and unnecessary clinical prescriptions, such as in the treatment for sore throat due to viral […]