A deficiency of taurine — a nutrient produced in the body and found in many foods — is a driver of aging in animals, according to a new study led by Columbia researchers and involving dozens of aging researchers around the world. The same study also found that taurine supplements can slow down the aging […]
A new study from the University of Michigan has revealed that the feeling of hunger itself may be enough to slow aging. These intriguing findings drove first author Kristy Weaver, Ph.D., principal investigator Scott Pletcher, Ph.D., and their colleagues to examine whether changes in the brain that prompt the drive to seek food could be […]
Exposure to female odors and pheromones causes weight loss and extends the life spans of mice, which may have implications for humans. “Our studies show that female odors slow the sexual development of female mice, but consequently extends their lifespan. And we also show that the smell of females can increase male mouse energy expenditure, […]
Researchers have long known that many animals live longer in colder climates than in warmer climates. New research in C. elegans nematode worms suggests that this phenomenon is tied to a protein found in the nervous system that controls the expression of collagens, the primary building block of skin, bone and connective tissue in many […]
Older cells may fail to make proteins or may make proteins that don’t function as they should, in a discovery that could lead to new drug targets to slow the ageing process. Payel Sen at the National Institutes of Health in Maryland previously found that control over gene expression breaks down in yeast and worm […]
Tissue remodeling is the reorganization of tissue architecture, which can be either physiological, responsible for directing the development and maintenance of tissues, or pathological, occurring after tissue injury. During wound repair initiated by an injury to the skin, cells migrating into the wound bed deposit a mass of granulation tissue to re-establish the barrier integrity […]
Finding and implementing preventive measures that can slow down the aging process is currently recognized as a major challenge of preventive medicine to combat the epidemic of age-dependent chronic diseases that is emerging as a result of a rapidly aging world population. Disparities in the pace of biological aging are already detectable at midlife indicating […]
Acne is among the most common skin diseases in the United States, according to the American Academy of Dermatology Association, affecting up to 50 million Americans each year. It is also among the least studied. It’s known that hair follicles assist in the development of a pimple, but new research suggests the skin cells outside […]
Partial reprogramming by expression of reprogramming factors (Oct4, Sox2, Klf4 and c-Myc) for short periods of time restores a youthful epigenetic signature to aging cells and extends the life span of a premature aging mouse model. However, the effects of longer-term partial reprogramming in physiologically aging wild-type mice are unknown. As organisms age, it is […]
Acne vulgaris is characterized by noninflammatory, open or closed comedones and by inflammatory papules, pustules, and nodules. Acne vulgaris typically affects the areas of skin with the densest population of sebaceous follicles; these areas include the face, the upper part of the chest, and the back. Acne vulgaris is the most common skin disease in […]