Vitiligo is an acquired pigmentary disorder of the skin that is characterized by circumscribed, depigmented macules and patches. The condition is frequently associated with disorders of autoimmune origin, with thyroid abnormalities being the most common. Initial lesions occur most frequently on the hands, forearms, feet, and face, favoring a perioral and periocular distribution. The lesions […]
Scald burns in children are a common presentation to the emergency department. Burn injury has devastating long-term physical, psychological, and financial consequences for the child and family. The ideal dressing would require a 1-time application in the emergency department and would relieve pain, be readily available, be inexpensive, expedite healing, and reduce scarring. Human amniotic […]
Acne is among the most common skin diseases in the United States, according to the American Academy of Dermatology Association, affecting up to 50 million Americans each year. It is also among the least studied. It’s known that hair follicles assist in the development of a pimple, but new research suggests the skin cells outside […]
Scleroderma with internal-organ involvement (diffuse cutaneous systemic sclerosis) is a devastating autoimmune disorder. Despite advances in management, mortality driven by pulmonary involvement has not changed in 40 years. Although disease-modifying antirheumatic drugs (DMARDs) and biologics have been studied, none have shown lasting benefit, and only cyclophosphamide given for 12 months has shown short-term benefit as […]
Therapies to target neuromuscular disorders affecting million of people worldwide are on the horizon thanks to research at the Montreal Clinical Research Institute of Montreal. Fusion of myoblasts, the stem cells responsible for the formation of skeletal muscles, could allow the repair of muscles damaged by diseases such as muscular dystrophy. The formation of muscles, […]
Today, by and large, patients receive a diagnosis of Alzheimer’s only after they exhibit well-known signs of the disease, such as memory loss. By that point, the best treatment options simply slow further progression of symptoms. But research has shown that the seeds of Alzheimer’s are planted years, even decades, earlier, long before the cognitive […]
Sometimes kids trip and fall, and their teeth take the hit. Nearly half of children suffer some injury to a tooth during childhood. When that trauma affects an immature permanent tooth, it can hinder blood supply and root development, resulting in what is essentially a “dead” tooth. Until now, the standard of care has entailed […]
A genetic defect is the most common cause of hearing loss at birth and in childhood. These hearing losses have a profound negative impact on daily living. Numerous causative genes for genetic hearing loss have been identified. However, at present, there are no truly curative therapies for this condition. When considering curative treatments for genetic […]
People with serious food allergies face potentially fatal consequences if they’re accidentally exposed to triggering foods. But tests in allergic mice show that swallowing a form of butyrate, a compound produced by healthy gut bacteria, offers protection against peanut allergy, scientists report. The treatment might also counteract other food allergies, as well as inflammatory diseases. […]
A new study from University of Louisville researchers in the Christina Lee Brown Envirome Institute has found that exposure to e-cigarette aerosols can cause heart arrhythmias in animal models, both in the form of premature and skipped heart beats. The study findings, published Oct. 25 in Nature Communications, suggest exposure to specific chemicals within e-cigarette […]