Small cell lung cancer accounts for about 15 percent of all diagnosed lung cancers and is still associated with a high mortality rate. SCLC tumours often develop resistance to chemotherapy and thus poor prognosis is due to tumour recurrence which occurs within only five to 14 months after initial diagnosis. As a recent research study […]
ASCT is typically preceded by induction therapy with chemotherapy to kill as many cancer cells as possible and induce a remission. For this study, the investigators selected patients with high-risk disease who still had active myeloma after induction therapy and before receiving ASCT, which constitutes a negative prognostic factor. “We focused on this patient population […]
An estimated 80% of older adults in the U.S. have high blood pressure. Maintaining healthy blood pressure can protect against serious conditions like heart failure, heart attacks, and strokes. A new study found that adding a relatively minimal amount of movement, about 3,000 steps per day, can significantly reduce high blood pressure in older adults. […]
People differ significantly in their memory performance. Researchers at the University of Basel have now discovered that certain brain signals are related to these differences. While it is well known that certain brain regions play a crucial role in memory processes, so far it has not been clear whether these regions exhibit different activities when […]
The search for functional natural compounds that can improve age-related cognitive decline has recently emerged as an important research focus to promote healthy aging. Trigonelline (TG), a plant alkaloid found in coffee, as well as in fenugreek seed and radish, was anticipated to possess cognitive enhancement properties. In this study, researchers led by the University […]
New research has revealed a potentially important role ginger supplements can play in controlling inflammation for people living with autoimmune diseases. The research published in JCI Insight focused on studying the impact of ginger supplementation on a type of white blood cell called the neutrophil. The study was especially interested in neutrophil extracellular trap (NET) […]
Guangzhou Institutes of Biomedicine and Health researchers have successfully created chimeric embryos containing a combination of human and pig cells. When transferred into surrogate pig mothers, the developing humanized kidneys had normal structure and tubule formation after 28 days. The work appears in the journal Cell Stem Cell. The researchers focused on kidneys because they […]
A healthy lifestyle that involves moderate alcohol consumption, a healthy diet, regular physical activity, healthy sleep and frequent social connection, while avoiding smoking and too much sedentary behaviour, reduces the risk of depression, new research has found. In research published today in Nature Mental Health, an international team of researchers, including from the University of […]
Researchers from the University of Arizona Cancer Center have identified a new method of activating specific molecules to target cancer cells while leaving healthy cells unharmed. In their recent study, published in the Journal of the American Chemical Society, Wei Wang, PhD, and his team developed a new strategy called click-release proteolysis targeting chimeras, or […]
A world-first discovery has revealed special immune cells called ‘killer T cells’ in older adults, directed against influenza viruses, closely resemble those found in newborns and children, but struggle to recognise infected cells — a finding that unlocks the potential for the development of better vaccines and therapies tailored to different age groups. Killer T […]