Author Archives: Karely Vega, MD

Changes in the Composition of Joint Lubricant May be Behind Osteoarthritis

Osteoarthritis is the most common joint disease in the United States, affecting an estimated 32.5 million adults. Osteoarthritis is caused by the wear and tear of the synovial joint, leading to the degeneration of the articular cartilage that forms the synovial joint. Studies suggest that changes in the composition of the synovial fluid reduce its […]

Scientists Find Potential New Targets to Treat Stroke

Scientists have been trying to find ways to minimize the damage following a stroke and speed up recovery. Now, a study led by scientists from Weill Cornell Medicine has found changes in gene activity in small blood vessels following a stroke.  The findings suggest that these changes could be targeted with existing or future drugs […]

Loss of Hair Color Linked to Stuck Stem Cells

Led by researchers from NYU Grossman School of Medicine, the new work focused on cells in the skin of mice and also found in humans called melanocyte stem cells, or McSCs.  Hair color is controlled by whether nonfunctional but continually multiplying pools of McSCs within hair follicles get the signal to become mature cells that […]

Implantable Device Shrinks Pancreatic Tumors

Houston Methodist nanomedicine researchers have found a way to tame pancreatic cancer — one of the most aggressive and difficult to treat cancers — by delivering immunotherapy directly into the tumor with a device that is smaller than a grain of rice. In a paper recently published in Advanced Science, Houston Methodist Research Institute researchers […]

Preventing Dangerous Blood Clots

Hibernating bears, paralyzed humans, and pigs kept in small enclosures all avoid dangerous blood clots, despite being immobile for extremely long periods. Research from the University of Reading, with partners in Denmark, Germany, Norway and Sweden, shows that reduction of a key protein prevents the formation of blood clots in all three mammal species when […]

Sugar Molecule in Blood Can Predict Alzheimer’s Disease

Early diagnosis and treatment of Alzheimer’s disease requires reliable and cost-effective screening methods. Researchers at Karolinska Institutet in Sweden have now discovered that a type of sugar molecule in blood is associated with the level of tau, a protein that plays a critical role in the development of severe dementia.  The study, which is published […]

New Genetic Target for Male Contraception Identified

Discovery of a gene in multiple mammalian species could pave the way for a highly effective, reversible and non-hormonal male contraceptive for humans and animals. Washington State University researchers identified expression of the gene, Arrdc5, in the testicular tissue of mice, pigs, cattle and humans. When they knocked out the gene in mice, it created […]

Time-Restricted Fasting Could Cause Fertility Problems

Time-restricted fasting diets could cause fertility problems according to new research from the University of East Anglia. The study published on April 12th, shows that time-restricted fasting affects reproduction differently in male and female zebrafish. Importantly, some of the negative effects on eggs and sperm quality can be seen after the fish returned to their […]

Promising Stem Cell Approach To Restore Vision In Eye Diseases

A preclinical study using stem cells to produce progenitor photoreceptor cells — light-detecting cells found in the eye — and then transplanting these into experimental models of damaged retinas has resulted in significant vision recovery.  This finding, by scientists at Duke-NUS Medical School, the Singapore Eye Research Institute and the Karolinska Institute in Sweden, marks […]

The Brain’s Support Cells May Play A Key Role In OCD

A type of cell usually characterized as the brain’s support system appears to play an important role in obsessive-compulsive disorder-related behaviors, according to new UCLA Health research published recently in Nature. The new clue about the brain mechanisms behind OCD, a disorder that is incompletely understood, came as a surprise to researchers.  They originally sought […]