Hidden HIV cells, known as latent infection, are responsible for the virus permanently remaining in the body and cannot be treated by current therapy options. These hibernating, infected cells are the reason why people living with HIV require life-long treatment to suppress the virus. Led by WEHI and The Peter Doherty Institute for Infection and […]
In the journal Angewandte Chemie, a research team has now introduced a completely new approach for treating herpes. Their method is based on the inhibition of an enzyme that is needed for the release of newly formed virus particles from infected cells. The majority of adults carry the instigator of herpes in their bodies because, […]
Chronic wounds pose significant challenges as they often fail to heal properly over time and can lead to complications associated with diabetes and vascular diseases. In severe cases, they may result in sepsis. Led by Professor Joo H. Kang, a team successfully developed a microfluidic system capable of processing blood into an artificial tissue scaffold. […]
Digesting a crunchy critter starts with the audible grinding of its rigid protective covering (the exoskeleton). Unpalatable as it may sound, the hard cover might be good for the metabolism, according to a new study, in mice. The researchers, led by Steven Van Dyken, PhD, found in mice that digesting chitin, an abundant dietary fiber […]
People who have had a stroke called an intracerebral hemorrhage who take cholesterol-lowering drugs called statins may have a lower risk of having another stroke, especially ischemic stroke, compared to people who also had an intracerebral hemorrhage but were not taking statins, according to a new study. “We looked at whether use of statins after […]
Resistant starch is a nondigestible fiber that ferments in the large intestine, and consumption of it has previously been shown to have a positive effect on metabolism in animal studies. NAFLD, caused by a buildup of fat in the liver, affects about 30% of the population worldwide. It can lead to severe liver diseases and […]
Scientists have discovered two new genes that cause head and neck cancer patients to be resistant to chemotherapy, and that silencing either gene can make cancer cells previously unresponsive to chemotherapy subsequently respond to it. The researchers looked through a chemical library, commonly used for drug discovery, and found two substances that could target the […]
PCOS affects 7-10% of women of childbearing age and is the most common cause of infertility. Women are diagnosed with PCOS if they have two of the following criteria: androgen excess (excess male sex hormones such as testosterone), ovulatory dysfunction and polycystic ovaries. “Our study found geographical differences in PCOS in black and white women, […]
A large study by researchers at Columbia University Mailman School of Public Health and the Norwegian National Institute of Public Health has identified molecular signatures of gestational inflammation linked to the risk of developing autism spectrum disorder (ASD). These findings, which provide insights into abnormal brain development, could eventually lead to a test to screen […]
Various medical circumstances, including heart attacks and extreme cases of COVID-19, necessitate the use of anticoagulants, medicines that prevent blood clots. But the most commonly used, heparin, can induce potentially fatal side effects by making the blood clots worse rather than better. For the first time, researchers have proposed a side-effect-free anticoagulating treatment that has […]