A key feature of the severe allergic reaction known as anaphylaxis is an abrupt drop in blood pressure and body temperature, causing people to faint and, if untreated, potentially die. That response has long been attributed to a sudden dilation and leakage of blood vessels. But Duke Health researchers have found that this response, especially […]
Researchers at the University of Birmingham, analyzed 20 studies which explored women and birthing people’s eating habits in the months before and shortly after conceiving a baby to see whether these studies showed evidence of association with a lower or higher chance of miscarriage. The Research team concluded that there is evidence to suggest a […]
Glaucoma is a neurodegenerative disease that causes vision loss and blindness due to a damaged optic nerve. Unfortunately, there is currently no treatment. In a newly published paper, researchers found neurons use mitochondria for a steady source of energy, and restoring mitochondrial homeostasis in the diseased neurons can protect the optic nerve cells from being […]
Researchers have found differences in the gut microbiomes of people with myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) compared to healthy controls. ME/CFS is a serious, chronic, and debilitating disease characterized by a range of symptoms, including fatigue, post-exertional malaise, sleep disturbance, cognitive difficulties, pain, and gastrointestinal issues. The causes of the disease are unknown and there […]
Heparin has long been used as a blood thinner, or anticoagulant, for patients with blood clotting disorders or after surgery to prevent complications. But the medication remains difficult to dose correctly, potentially leading to overdosing or underdosing. A team of Penn State researchers combined heparin with a protein fragment, peptide, to slow down the release […]
In virtually all persons with amyotrophic lateral sclerosis (ALS), a protein called TDP-43 is lost from its normal location in the nucleus of the cell. This triggers the loss of stathmin-2, a protein crucial to regeneration of neurons and the maintenance of their connections to muscle fibers, essential to contraction and movement. In the study […]
The behavioral disorders observed in autism are associated with a multitude of genetic alterations. Scientists from the Hector Institute for Translational Brain Research (HITBR) have now found another molecular cause for this condition. The transcription factor MYT1L normally protects the molecular identity of nerve cells. Disorders from the autism spectrum (ASD, autism spectrum disorders) are […]
Researchers from Indiana University School of Medicine have successfully developed a blood test for anxiety. The test examines biomarkers that can help them objectively determine someone’s risk for developing anxiety, the severity of their current anxiety and which therapies would likely treat their anxiety the best. “Many people are suffering from anxiety, which can be […]
Information available at birth may help to identify children with higher likelihood of developing ADHD, according to new research from RCSI University of Medicine and Health Sciences. The Adolescent Brain Cognitive Development (ABCD) study is an ongoing study of children in the US, born between 2005 and 2009. Children were enrolled to the study at […]
Researchers at Karolinska Institutet in Sweden now show that the immune system of people with diabetes has lower levels of the antimicrobial peptide psoriasin, which compromises the urinary bladder’s cell barrier, increasing the risk of urinary tract infection. Diabetes is a common disease that affects health in many ways, one effect is that it compromises […]