Category Archives: Regenerative Medicine News and General Information

Researchers at the Princess Margaret Cancer Centre have made new findings which provide a broader understanding of how dormant hematopoietic stem cells are activated and could pave the way towards therapeutic treatments for a number of cancers.  The team of researchers studied lysosomes, which are membrane-bound organelles found in all cells. They were once believed […]

Pain starts in receptor nerve cells found beneath the skin and in organs throughout the body. When you are sick, injured, or have other types of problems, these receptor cells send messages along nerve pathways to the spinal cord, which then carries the message to the brain. Pain medicine reduces or blocks these messages before […]

It’s long been believed that advancing age leads to broad declines in our mental abilities. Now new research offers surprisingly good news by countering this view.  The findings, published on August 19, 2021, in Nature Human Behaviour, show that 2 key brain functions, which allow us to attend to new information and to focus on […]

An international study, published in the journal of Science, has found that, after accounting for body size, energy expenditure peaks in infancy and then steadily declines until the age of about 20 years. Contrary to the popular belief that metabolism slows in middle age, the research suggests that energy expenditure does not change until close […]

Regenerative medicine has yet to designate biomarkers that can identify patients likely to respond to a stem cell therapy based on their expression of a clinical or molecular profile congruent with the therapeutic mechanism-of-action (MOA) of the stem cell for that condition, while withholding treatment from likely non-responders. Ultimately, such patient stratification will be required […]

Modern health care is not only reliant on antibiotics to treat infectious disease but also to prevent infections during surgery or immune suppression. Escalating levels of antibiotic resistance impose a substantial burden on medical practice. It is generally believed the evolution of antibiotic resistance is an inevitable consequence of antibiotic use. Antibiotic resistance is the […]

Obesity is on the rise worldwide. According to the World Health Organization (WHO), nearly 2 billion adults are currently overweight and 650 million of them have obesity. A study from the University of South Australia found that some types of obesity can lead to a reduction in the brain’s gray matter and investigated its association […]

Understanding how resistance to chemotherapy occurs could lead to better anticancer treatments. Persister cells in tumors can contribute to this resistance. Cancer can recur when a subset of tumor cells called persister cells survive chemotherapy. Most of these cells are non-dividing (quiescent) in the presence of therapeutic drugs, but a rare subpopulation can re-enter the […]

Malignant stem cells in the gut secrete factors that promote the differentiation of neighboring stem cells, thereby aiding the replacement of normal stem cells by those with cancer-promoting mutations. In recent years there has been growing recognition that the surrounding tissue environment affects the natural selection of these mutation-driven characteristics. The effects of interactions between […]

A stem cell drug was approved for market authorization for the first time in history. Prochymal (remestemcel-L) is also the first drug approved for the treatment of acute graft vs host disease (GvHD) in children. GvHD is a devastating complication of bone marrow transplantation that kills almost 80% of all affected children, many of which […]