Category Archives: Regenerative Medicine News and General Information

MS is a progressive neurological disease that currently has no cure. It is associated with a wide-range of debilitating symptoms, including problems with coordination, cognition, muscle weakness and depression. CAMH-led pre-clinical studies using a small molecule drug have shown promise as a potential new treatment for multiple sclerosis (MS).  Expanding on Dr. Fang Liu’s earlier […]

According to the World Health Organization (WHO), dementia affects more than 55 million people worldwide, and there are around 10 million new cases every year. The most common form of dementia is Alzheimer’s disease, which causes around 70% of cases. Now, a comprehensive review of the evidence, published in The Journal of Alzheimer’s Disease, has […]

Glioblastoma is one of the most treatment-resistant cancers, with those diagnosed surviving for less than two years. In a new study in NPJ Genomic Medicine, researchers at the University of Notre Dame have found that a largely understudied cell could offer new insight into how the aggressive, primary brain cancer is able to resist immunotherapy. […]

Comparing PET scans of more than 90 adults with and without mild cognitive impairment (MCI), Johns Hopkins Medicine researchers say relatively lower levels of the so-called “happiness” chemical, serotonin, in parts of the brain of those with MCI may play a role in memory problems including Alzheimer’s disease. “The study shows that people with mild […]

A preclinical study shows that a specific human genetic variant of a receptor that stimulates insulin release may help individuals be more resistant to obesity.  The study provides new insight into how human genetic variations affect an individual’s susceptibility to weight gain. The researchers developed mice with a human genetic variant in the glucose-dependent insulinotropic […]

The ketogenic diet proved to be effective at controlling polycystic kidney disease (PKD) in the first randomized controlled clinical trial of ketogenic metabolic therapy for PKD. The researchers’ study is published in the journal Cell Reports Medicine. For PKD patients, these findings represent an opportunity to control a genetic disease that leads to a progressive […]

A landmark study has shown that severe asthma can be controlled using biologic therapies, without the addition of regular high-dose inhaled steroids which can have significant side effects. The findings from the multinational SHAMAL study, published in The Lancet, demonstrated that 92% of patients using the biologic therapy benralizumab could safely reduce inhaled steroid dose […]

Microgels form a thin protective shell around a droplet until the temperature rises above 32 degrees. Then the microgels shrink and the droplet dissolves in the surrounding liquid. A study now reveals the underlying mechanism behind this process. The discovery could revolutionize methods of targeting medicines to specific locations within the body. Emulsions consist of […]

Researchers discovered distinct mechanisms controlling different types of immune cells, and found that, by precisely targeting these mechanisms, they could selectively eliminate ‘problematic cells’ and reshape the skin’s immune landscape. Our skin is packed with specialized immune cells that protect against infections and cancer and promote healing. These cells, called tissue-resident T cells or TRM […]

Researchers report that medications that promote slow to moderate weight loss may improve survival rates for people with weight issues who also have knee or hip osteoarthritis. Rapid weight loss prompted by anti-obesity drugs may increase the chance of premature death among people with weight issues who also have knee or hip osteoarthritis, according to […]