Relief could be on the way for people with painful hand osteoarthritis after a Monash University and Alfred Health-led study found an affordable existing drug can help. Until now there has been no effective treatment. Published in The Lancet, the paper investigated methotrexate, a low-cost, effective treatment for inflammatory joint conditions such as rheumatoid arthritis […]
Cystic fibrosis is one of the most common fatal hereditary diseases worldwide. As many as 8,000 children, teens, and adults are living with the disease in Germany today. An imbalance in salt and water transport across mucosal surfaces of the body causes people with cystic fibrosis to produce thick, sticky secretions that harm organs such […]
Osteoarthritis (OA) is the most common form of arthritis and is among the top 10 conditions contributing to Years Lived with Disability — a measure reflecting the impact an illness has on quality of life before it resolves or leads to death. To date, no treatments are approved that slow disease progression. Researchers from Boston […]
Per- and polyfluoroalkyl substances (PFAS) have become ubiquitous throughout the environment, and increasing evidence has demonstrated their deleterious effects. A group of smaller, fluorinated compounds are becoming replacements for these “forever chemicals,” though research suggests the smaller versions could also be harmful. Now, a study in ACS’ Environmental Science & Technology reports that the levels […]
Gestational diabetes is a global health issue affecting almost 3 million pregnant women worldwide every year. It is a condition characterized by elevated blood sugar levels during pregnancy, posing increased health risks for both mothers and their babies. Professor Fidelma Dunne, Professor of Medicine at University of Galway and Consultant Endocrinologist at Saolta University Health […]
Generating specific cell lineages from induced pluripotent stem cells and embryonic stem cells is the holy grail of regenerative medicine. Guiding iPSCs toward a target cell line has garnered much attention, but the process remains challenging. Now, researchers from Japan have discovered that an anti-nucleolin DNA aptamer, iSN04, can determine a cell’s lineage during differentiation. […]
Pregnancy complications such as preeclampsia and gestational diabetes have recently been associated with a higher risk of developing heart disease later in life. But a new Northwestern Medicine study has found obesity before or during pregnancy is the actual root cause of future cardiovascular disease. Prior to this study, scientists were unsure which factor — […]
Researchers from the United States, Brazil, and Spain, including scientists with the Fralin Biomedical Research Institute at VTC, published an analysis in a special edition of the British Medical Journal with a timely and controversial recommendation: It’s time for an international shift in the way we think about ultra-processed food. “There is converging and consistent […]
Scientists have uncovered why night shift work is associated with changes in appetite in a new University of Bristol-led study. The findings, published in Communications Biology, could help the millions of people that work through the night and struggle with weight gain. Scientists from Bristol and the University of Occupational and Environmental Health in Japan, […]
Huntington’s disease is among the so-called polyglutamine (polyQ) diseases, a group of neurodegenerative disorders caused by multiple repetitions of glutamine amino acids in specific proteins. Huntington’s disease is an inherited condition that causes widespread deterioration in the brain and disrupts thinking, behavior, emotion and movement. In their recent study, Professor Dr David Vilchez (CECAD) and […]