Repetitive head impacts from tackle football can have long-term neurological consequences like chronic traumatic encephalopathy (CTE). But research on the association between participation in tackle football and PD is limited. In the largest study to describe the association between participation in football and the odds for having a reported diagnosis of PD, researchers from the […]
Researchers from Brigham and Women’s Hospital have designed a probiotic to suppress autoimmunity in the brain, which occurs when the immune system attacks the cells of the central nervous system. Autoimmunity in the brain is at the core of several diseases, including multiple sclerosis. “When a drug is taken, its concentration in the bloodstream peaks […]
Long COVID can persist for at least a year after the acute illness has passed, or appear months later, according to the most comprehensive look yet at how symptoms play out over a year. The multicenter study, a collaboration between UC San Francisco, the Centers for Disease Control and Prevention (CDC) and seven other sites, […]
Viral infections, autoimmune disease, and other conditions can cause platelet levels to drop throughout the body, termed thrombocytopenia. After a robust clinical and research collaboration, Stephan Moll, MD, and Jacquelyn Baskin-Miller, MD, both in the UNC School of Medicine, have linked adenovirus infection with a rare blood clotting disorder. This is the first time that […]
Researchers have developed a gene therapy that treats chronic pain by indirectly regulating a specific sodium ion channel, according to a new study published. The innovative therapy is made possible by the discovery of the precise region where a regulatory protein binds to the NaV1.7 sodium ion channel to control its activity. Sodium ion channels […]
Bones can repair themselves after a minor break or fracture, leaving us as good as new. Unfortunately, after a larger injury bones often don’t heal well. Although there are many different ways to improve bone repair over larger areas in animal models, very few techniques translate well into the clinic. A research team decided to […]
For the first time, scientists have shown that gut bacteria differences are associated with later development of juvenile idiopathic arthritis, a debilitating rheumatic childhood disease, and that these differences are present years before the disease is diagnosed. The research team made this discovery by analyzing stool samples from one-year-old children in a long-term study called […]
Chronic exposure to fine particulate air pollutants and nitrogen dioxide may increase non-lung cancer risk in older adults, according to a study led by Harvard T.H. Chan School of Public Health. “Our findings uncover the biological plausibility of air pollution as a crucial risk factor in the development of specific cancers, bringing us one step […]
Gait-related disturbances adversely affect the quality of life of patients with Parkinson’s disease (PD), a condition affecting millions worldwide. Although various pharmacological, surgical, and rehabilitative treatments exist, their effectiveness is limited. Now, a team of researchers from Japan has successfully addressed this limitation. Using a novel neuromodulation approach that incorporates gait-combined closed-loop transcranial electrical stimulation, […]
Scientists have discovered what they believe to be the central mechanism behind cognitive decline associated with normal aging. “The mechanism involves the mis-regulation of a brain protein known as CaMKII which is crucial for memory and learning,” said the study’s co-senior author Ulli Bayer, PhD.”This study directly suggests specific pharmacological treatment strategies.” Using mouse models […]