Houston Methodist nanomedicine researchers have found a way to tame pancreatic cancer — one of the most aggressive and difficult to treat cancers — by delivering immunotherapy directly into the tumor with a device that is smaller than a grain of rice. In a paper recently published in Advanced Science, Houston Methodist Research Institute researchers […]
Hibernating bears, paralyzed humans, and pigs kept in small enclosures all avoid dangerous blood clots, despite being immobile for extremely long periods. Research from the University of Reading, with partners in Denmark, Germany, Norway and Sweden, shows that reduction of a key protein prevents the formation of blood clots in all three mammal species when […]
A research team led by the University of Michigan Health Department of Neurology followed more than 120 patients who underwent bariatric surgery for obesity over two years after the procedure. They found that all metabolic risk factors for developing diabetes, such as high glucose and lipid levels, improved outside of blood pressure and total cholesterol. […]
Early diagnosis and treatment of Alzheimer’s disease requires reliable and cost-effective screening methods. Researchers at Karolinska Institutet in Sweden have now discovered that a type of sugar molecule in blood is associated with the level of tau, a protein that plays a critical role in the development of severe dementia. The study, which is published […]
Discovery of a gene in multiple mammalian species could pave the way for a highly effective, reversible and non-hormonal male contraceptive for humans and animals. Washington State University researchers identified expression of the gene, Arrdc5, in the testicular tissue of mice, pigs, cattle and humans. When they knocked out the gene in mice, it created […]
Post-traumatic stress disorder in U.S. military members frequently follows a concussion-like brain injury. “Is one causing the other, and how does that occur?” asked senior author Michael Fanselow. Two groups of rats were studied. Through surgery, a concussion-like brain injury was produced in 19 of the rats. Sixteen other rats also had the surgery, but […]
Knee joint injuries are typically related to sports, but people often do not know that such injuries may lead to joint inflammation and post-traumatic osteoarthritis. The study presents a new mechanobiological model for cartilage degeneration by implementing tissue deformation and fluid flow as mechanisms for cartilage breakdown when a normal dynamic loading, such as walking, […]
A type of cell usually characterized as the brain’s support system appears to play an important role in obsessive-compulsive disorder-related behaviors, according to new UCLA Health research published recently in Nature. The new clue about the brain mechanisms behind OCD, a disorder that is incompletely understood, came as a surprise to researchers. They originally sought […]
Medical advice for individuals with mild-to-moderate infections generally involves getting adequate rest and increasing fluid intake. Interestingly, a recent study published in the journal Brain, Behavior, and Immunity suggests that repeated inflammation caused by the administration of a bacterial toxin to middle-aged mice led to cognitive deficits. These cognitive deficits were also accompanied by changes […]
Prostate cancer is the second-leading cause of cancer death among men in the United States; about 33,330 men are expected to die of the disease this year. Most prostate cancers remain confined to the prostate and can be successfully managed by active surveillance or local therapy, with five-year survival rates above 99%. But once prostate […]