Since early May 2022, many countries in Europe, as well as Australia, and the U.S. have reported an increased number of monkeypox cases. In the U.K., 20 monkeypox cases have been confirmed since early May. As of May 19, Canada confirmed two monkeypox cases and said it was investigating 17 suspected cases. What is Monkeypox? […]
Canada legalized recreational cannabis in October of 2018. However, it has been legal for medical purposes since 2001, with over 230,000 individuals having acquired medical client registrations by early 2018. Cannabis is a popular alternative or complementary therapy among people with multiple sclerosis (MS), whose use of cannabis has been estimated as high as four […]
Only some organs have intrinsic repair and regenerative capacity in the human body, and different organs often show different rates of repair and regeneration, such as the peripheral nervous system. Sciatic nerve injury is a common peripheral neuropathy usually caused by trauma, indicating the loss of motor and sensory functions. Patients suffering from such injury […]
As the population continues to age, a pandemic of Parkinson’s disease (PD) is emerging, with conservative estimates of over 14 million victims globally by 2040. While PD patients display a wide range of non-motor features, the defining symptoms are progressive motor deficits due to striatal dopaminergic insufficiency secondary to loss of dopaminergic nigral neurons. Current […]
Chronic inflammatory diseases are the leading cause of mortality worldwide. Inflammation is part of the host’s complex defense mechanism. It is the immune system’s biological response against different infectious or non-infectious stimuli. These stimuli may activate inflammatory signaling pathways such as nuclear factor-kappa B (NF-κB), mitogen-activated protein kinase (MAPK), and Janus kinase signal transducer and […]
Guidelines recommend radical cystectomy with pelvic lymphadenectomy for aggressive bladder cancer, which is a complex procedure with an estimated 33,429 operations performed in the US from 2008 to 2011 and 3,043 in England in 2015. Survival following radical cystectomy reflects tumor biology, treatment received, and patient fitness. Morbidity from complications after cystectomy can be considerable. […]
Animal studies have demonstrated that diets that severely restrict total calorie intake while providing all the essential nutrients can extend the average lifespan. Animal studies have revealed that the timing of calorie restriction can have an effect due to the circadian system, which controls daily cycles of physiology, metabolism, and behaviors such as eating. This […]
Older adults (aged 60 years) are the fastest-growing age group in the world and are projected to represent 1 in every 4 adults by 2050. Aging is associated with a progressive loss of muscle mass and strength that manifests as reduced physical performance and endurance capacity, imposing a burden on both the individual and society. […]
Despite the progress in medicine, the etiology of inflammatory bowel diseases (IBD), which are primarily Crohn’s disease (CD) and ulcerative colitis (UC), still remains unclear. What is more, the incidence of IBD, especially CD, is still increasing and the highest rates are found in the industrialized countries. It is believed that the disease process develops […]
Evidence indicates that a high-fat diet can promote gut inflammation and increase gut permeability. The use of antibiotics further exacerbates these complications and can lead to the development of inflammatory bowel disease. Inflammatory bowel disease (IBD) is an umbrella term used to describe disorders that involve chronic inflammation of your digestive tract. There are two […]