High blood pressure, or hypertension, is the most common primary diagnosis in the United States, and it is one of the most common worldwide diseases afflicting humans and is a major risk factor for stroke, myocardial infarction, vascular disease, and chronic kidney disease. Despite extensive research over the past several decades, the etiology of most […]
The extraembryonic mesoderm (EXM) is an important tissue with essential roles in development. EXM is implicated in primitive erythropoiesis and extracellular matrix formation; becomes an integral part of the amnion, yolk sac, allantois, and chorion; and forms the primitive umbilical cord. When all goes well, a human embryo implants in the womb about seven days […]
Neutrophils, the most abundant circulating leukocytes in humans, accumulate in many types of tumors and represent a significant portion of tumor-infiltrating cells. Due to their heterogeneity and plasticity in the tumor microenvironment (TME), neutrophils have demonstrated contradictory protumor and antitumor effects during tumor evolution. For instance, tumor-associated neutrophils present direct or antibody-dependent cytotoxicity against solid […]
How many times do we hear that you need an intense workout to see results in the short-term? or that you need to spend several hours in the gym to improve your strength and muscle thickness?. Well , latest research indicates a little bit of daily activity could well be the most beneficial approach, at […]
Obesity affects more than 41% of all adults in the U.S. and increases the risk of heart disease, stroke, diabetes, and certain types of cancer. Most treatments for obesity focus on eating habits and physical activity. Scientists have long known that serotonin, a chemical messenger found throughout the brain and body, plays a key role […]
Age-related macular degeneration (AMD or ARMD) is the most common cause of irreversible vision loss in the developed world. AMD is associated with the presence of drusen, without visual loss early in the disease. However, the disease often slowly progresses over years to retinal atrophy and central retinal degeneration with associated loss of central vision. […]
Heart failure is a progressive condition in which the heart loses its ability to pump enough blood to meet the body’s needs. It’s one of the most common causes of disability and death in developed countries, with more than 6 million adults living with heart failure in the U.S. alone, according to the Centers for […]
Over the past decades, the incidence of chronic inflammatory disorders such as autoimmune and type 2 allergic diseases has increased worldwide. A growing body of evidence indicates that this rapid and relatively recent onset of allergic epidemics is the consequence of environmental and behavioral changes collectively known as the “westernized lifestyle” More recently, it was […]
Dementia is considered a major neurocognitive disorder, in which a deficit in cognitive functioning is acquired rather than developmental. Dementia is most common in elderly individuals, with advancing age being the strongest risk factor. There are many types of this condition such as Alzheimer Dementia (AD) and Vascular Dementia (VD) , among others of all-cause […]
Obesity is the most prevalent nutritional disorder among children and adolescents in the United States. Approximately 21-24% of American children and adolescents are overweight, and another 16-18% is obese; the prevalence of obesity is highest among specific ethnic groups. Childhood obesity predisposes to insulin resistance and type 2 diabetes, hypertension, hyperlipidemia, liver and renal disease, […]