Monthly Archives: August 2023

Scientists have found that an enzyme called Fumarate Hydratase is repressed in macrophages, a frontline inflammatory cell type implicated in a range of diseases including Lupus, Arthritis, Sepsis and COVID-19. Professor Luke O’Neill, says: “No-one has made a link from Fumarate Hydratase to inflammatory macrophages before and we feel that this process might be targetable […]

Scientists have discovered an additional potential cause of the genetic mutations that result in rare conditions such as Huntington’s disease (HD). The neurodegenerative diseases usually are inherited, given that the expansion of CAG repeats in a gene can be passed down the generations. Previously, it had been thought the damage in these genetic diseases was […]

A simple blood test may predict the risk of progressive heart and kidney disease in people with Type 2 diabetes and kidney disease, according to new research published today in the American Heart Association’s flagship journal Circulation. “Treatment with canagliflozin, a sodium glucose co-transporter 2 inhibitor, lowered biomarker levels and reduced the risk of hospitalization […]

Pre-clinical trials by University of Queensland researchers have found an injection of a specific blood factor can replicate the benefits of exercise in the brain. Dr Odette Leiter and Dr Tara Walker from UQ’s Queensland Brain Institute led a team which discovered platelets, the tiny blood cells critical for blood clotting, secrete a protein that […]

A deaf adult cannot recover the ability to hear, because the sensory hearing cells of the inner ear don’t regenerate after damage. In two new studies, scientists explain why this is the case and how we might be able to change it. “In the non-sensory supporting cells of the inner ear, key genes required for […]