Disease of the small airways in the lungs is a potential long-lasting effect of COVID-19, according to a new study. The study found that small airways disease occurred independently of initial infection severity. The long-term consequences are unknown. “There is some disease happening in the small airways independent of the severity of COVID-19,” said study […]
Many individuals with kidney dysfunction develop anemia, or a shortage of healthy red blood cells that carry oxygen to the body’s tissues. Some treatments for anemia are linked with serious cardiovascular side effects, but a new class of oral drugs called hypoxia inducible factor-prolyl hydroxylase inhibitors may be comparable to placebo in these trials. These […]
Hard-to-detect colorectal pre-cancerous lesions known as serrated polyps, and the aggressive tumors that develop from them, depend heavily on the ramped-up production of cholesterol, according to a preclinical study from researchers at Weill Cornell Medicine. The finding points to the possibility of using cholesterol-lowering drugs to prevent or treat such tumors. In the study, published […]
New research reveals that neurons in the preoptic hypothalamus — the region of the brain that regulates sleep and body temperature — are rhythmically activated during non-rapid eye movement sleep (NREM). Stress activates these brain cells out of turn, causing “microarousals,” that interrupt sleep cycles and decrease the duration of sleep episodes, according to research […]
A protein in the immune system programmed to protect the body from fungal infections is also responsible for exacerbating the severity of certain autoimmune diseases such as irritable bowel disease (IBS), type 1 diabetes, eczema and other chronic disorders, new research from The Australian National University (ANU) has found. The discovery could pave the way […]
MS is a progressive neurological disease that currently has no cure. It is associated with a wide-range of debilitating symptoms, including problems with coordination, cognition, muscle weakness and depression. CAMH-led pre-clinical studies using a small molecule drug have shown promise as a potential new treatment for multiple sclerosis (MS). Expanding on Dr. Fang Liu’s earlier […]
According to the World Health Organization (WHO), dementia affects more than 55 million people worldwide, and there are around 10 million new cases every year. The most common form of dementia is Alzheimer’s disease, which causes around 70% of cases. Now, a comprehensive review of the evidence, published in The Journal of Alzheimer’s Disease, has […]
Glioblastoma is one of the most treatment-resistant cancers, with those diagnosed surviving for less than two years. In a new study in NPJ Genomic Medicine, researchers at the University of Notre Dame have found that a largely understudied cell could offer new insight into how the aggressive, primary brain cancer is able to resist immunotherapy. […]
Comparing PET scans of more than 90 adults with and without mild cognitive impairment (MCI), Johns Hopkins Medicine researchers say relatively lower levels of the so-called “happiness” chemical, serotonin, in parts of the brain of those with MCI may play a role in memory problems including Alzheimer’s disease. “The study shows that people with mild […]
A preclinical study shows that a specific human genetic variant of a receptor that stimulates insulin release may help individuals be more resistant to obesity. The study provides new insight into how human genetic variations affect an individual’s susceptibility to weight gain. The researchers developed mice with a human genetic variant in the glucose-dependent insulinotropic […]