Osteoarthritis (OA) is a leading cause of severe long-term pain and disability affecting approximately 10% of the global population. Regenerative solutions and new tissue engineering based strategies are promising for treatment of moderate OA. Current research for treatment of knee OA with PRP is promising; however, there is a lack of consensus regarding the preparation […]
The coronavirus sports a luxurious sugar coat. “It’s striking,” thought Rommie Amaro, staring at her computer simulation of one of the trademark spike proteins of SARS-CoV-2, which stick out from the virus’s surface. It was swathed in sugar molecules known as glycans. Many viruses have glycans covering their outer proteins, camouflaging them from the human […]
Type 2 diabetes mellitus (T2DM) is one of the leading causes of death in the world. The number of patients with this disease has dramatically increased, especially in developing countries. The International Diabetes Federation estimated that the diabetes population will reach 380 million globally by 2025. Perhaps as a result of increased bad diet habits […]
A groundbreaking study found that stem cells reduce the amount of virus causing AIDS, boost the body’s antiviral immunity and restore the gut’s lymphoid follicles damaged by HIV. This provided a strategy in the eradication of HIV. Although antiretroviral therapy can suppress HIV replication, it does not eliminate viral reservoirs or restore damaged lymphoid tissue, […]
Our body is made up of millions of cells. As we age our cells do the same and there is a point when they stop replicating and dividing until they eventually die. Scientists have long known that genes influence how cells age and how long humans live, but the exact mechanism remains unknown. A new […]
As we all are well aware, a recent worldwide outbreak (pandemic) of pneumonia caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) ranges from asymptomatic or mild upper respiratory tract infection to severe pneumonia, ARDS or even death. The nasal epithelium was found to be the first site of infection and transmission among individuals with […]
Mesenchymal stem cells (MSCs) are multipotent cells that can be isolated from various adult tissues such as the bone marrow, umbilical cord, adipose, peripheral blood, liver and tooth root. MSCs bring new enthusiasm for regenerative medicine and immune disorder-related diseases because they are convenient to isolate, have strong self-renewal abilities and have multipotent differentiation abilities. […]
Acute Respiratory Distress Syndrome (ARDS) is a rapid onset of diffuse lung injury arising from a variety of insults, along with refractory hypoxemia ranging from mild to severe. It can lead to a devastating hypoxemic respiratory failure, characterized by disruption of the alveolar-capillary membrane barrier. The current management of this condition remains supportive, and includes […]
Muscle Stem Cells also known as Satellite cells are needed in order to have muscle hyperplasia, hypertrophy or repair of muscle tissue. Understanding the linkage between Stem cell activity and dietary components is a timely area of research. Whether simply elucidating the influence of dietary constituents on the Satellite cell proliferation and differentiation, or regenerating […]
The oral cavity is colonized by billions of bacteria, fungi, and even viruses, now known as oral microbiomes. It is well known that the oral microbial community includes pathogenic bacteria and probiotics, and that the homeostasis of oral microbiomes plays a crucial role in maintaining the well being and healthy status of a human. There […]