Pacific whiting is caught in large volumes in the United States but consumers have little familiarity with the mild, white meat fish also known as hake. The gelatin in the skin of Pacific whiting, an abundant fish on the Pacific Coast of North America, may help prevent skin wrinkling caused by ultraviolet radiation, a new […]
The use of facial rejuvenation treatments continues to grow worldwide. Almost all current therapies are based on the implantation of foreign substances, such as hyaluronic acid, bovine, porcine, or recombinant collagens, etc., and the generation of wound-healing cascades through ablative skin surfacing or chemical peeling. The use of cell therapies is also growing for many […]
During the last decade, there has been an increased appreciation of the influence of the host microbiome composition and functionalities on human cellular processes, such as gut and skin health and immunity, but also visible aging of the skin. During aging, the human skin changes macroscopically and microscopically. Wrinkle formation, reduced elasticity and wound healing, […]
Older adults (aged ≥60 years) are the fastest-growing age group in the world and are projected to represent 1 in every 4 adults by 2050. Aging is associated with a progressive loss of muscle mass and strength that manifests as reduced physical activity performance and endurance capacity, imposing a burden on both the individual and […]
What is Metformin Used for? Metformin is the most widely-prescribed oral hypoglycemic medication for type 2 diabetes worldwide. In 1922, synthesis of metformin and related biguanide compounds phenformin and buformin was achieved by Werner and Bell, paving the way for metformin to attain widespread use in humans as first-line therapy for type 2 diabetes (T2D) […]
Selenium is an essential trace mineral found in soil, water, and some foods. It is an important factor in many body processes. Studies have suggested that it has anti-aging properties and may even protect against age-related diseases. This mineral is naturally present in the body, it gets stored in muscle tissue, though the thyroid is […]
A new study has uncovered how genetic changes accumulate slowly in blood stem cells throughout life and how they are likely responsible for the dramatic change in blood production after the age of 70. Age-related change in human hematopoiesis causes reduced regenerative capacity, cytopenias, immune dysfunction, and increased risk of blood cancer. However, the reason […]
In a recently published study, researchers evaluated the use of cerebrospinal fluid (CSF) transferred from younger to older mice and its effect on the aging brain. The study appears in the journal Nature. For the study, the researchers conditioned mice to remember an event so they could test this memory later. They used 20-month-old mice […]
Animal studies have demonstrated that diets that severely restrict total calorie intake while providing all the essential nutrients can extend the average lifespan. Animal studies have revealed that the timing of calorie restriction can have an effect due to the circadian system, which controls daily cycles of physiology, metabolism, and behaviors such as eating. This […]
Aging is characterized by declining cell, tissue, and organ function and increased susceptibility to chronic and debilitating diseases. Comprising bacteria, viruses, fungi, protozoa, and archaea, the intestinal microbiota contributes to the life-long health of the host, playing key roles in the development and maintenance of the host immune system and the intestinal epithelial barrier. During […]