Depression affects 264 million persons in the world, accounting for some 4.3% of the global burden of disease. Major depressive disorder has significant potential morbidity and mortality, contributing to suicide, incidence and adverse outcomes of medical illness, disruption in interpersonal relationships, substance abuse, and lost work time. During 2009–2012, 7.6% of Americans aged 12 and […]
Vitamin D is a pro-hormone and an essential micronutrient, and although its classical roles are related to the regulation of calcium homeostasis, various types of immune cells express both the vitamin D receptor and metabolizing enzymes, suggesting that hormonal vitamin D could also play a role in modulating inflammatory responses. This is supported by an […]
Old adult population has been increasing thanks to longevity. The accompanying increased prevalences of chronic illnesses, loss of musculoskeletal mass, frailty, and bone fragility increase the risk of falls and fractures. Loss of independence increases the number of people needing full time institutionalized care, the source of around 30% of all hip fractures in the […]
The rising prevalence of childhood obesity in US children has led to a parallel rise in the prevalence of prediabetes and overt type 2 diabetes. Prediabetes is well characterized in adults but less so in children and adolescents: the factors that determine the progression of prediabetes to T2D or its reversion to normoglycemia are poorly […]
Homocysteine (Hcy) is an important amino acid in your blood that helps create proteins. Hyperhomocysteinemia (HHcy) is a metabolic disorder mainly due to improper removal or accumulation of homocysteine most commonly arising from low dietary intake of Folate (Fol) or Vitamin B12 (B12), those last two vitamin can break down the levels of homocysteine and […]
There has been a growing body of evidence associating consumption of ultra-processed foods (UPF) with adverse health outcomes including depression, cardiovascular disease, and all-cause mortality. UPFs are high in sugar, fat, and salt and low in protein and fiber. Some examples are soft drinks, salty and sugary snacks, ice cream, sausage, deep-fried chicken, yogurt, canned […]
Atopic eczema is an inflammatory skin disease that can substantially impact affected individuals. It is more common in children, often developing before their first birthday. It’s usually a long-term (chronic) condition, although it can improve significantly, or even clear completely, in some children as they get older. There is increasing evidence that atopic eczema partly […]
Low-grade systemic inflammation is associated with an increased risk of various diseases, including cardiovascular disease (CVD) and cancer. Modifiable factors can reduce inflammation and potentially modulate disease risk. One of these factors is dietary fiber intake, in which higher intakes have been associated with lower systemic inflammation in various studies, in both healthy adults and […]
Resistant starch is a type of carbohydrate that doesn’t get digested in the small intestine. Instead, it ferments in your large intestine and feeds beneficial gut bacteria. This type of starch provides numerous health benefits and has fewer calories than regular starch, having only 2 calories per gram, while regular starches contain 4 per gram. […]
Diabetes is a major global health concern, affecting mortality rates and the quality of life of those with the condition and their families. There were an estimated 463 million people with diabetes in the world in 2019, of whom 90% to 95% have type 2 diabetes. By 2045, it is estimated that there will be […]