Pneumonia is an infection of the lung alveoli caused by bacteria, viruses or fungi. The microbial ecosystem (or microbiome) of the human respiratory tract colonizes different niches. Scientists from the Institut Pasteur and the CNRS have demonstrated that the microbiome composition, pathogen load and clinical interventions influence the severity of bacterial pneumonia caused by Legionella […]
Chronic wounds pose significant challenges as they often fail to heal properly over time and can lead to complications associated with diabetes and vascular diseases. In severe cases, they may result in sepsis. Led by Professor Joo H. Kang, a team successfully developed a microfluidic system capable of processing blood into an artificial tissue scaffold. […]
New research from Rice University finds that antidepressants may actually reduce negative memories in individuals suffering from depression while improving overall memory function. The study, “Perceived antidepressant efficacy associated with reduced negative and enhanced neutral mnemonic discrimination,” appears in the latest edition of Frontiers in Human Neuroscience. It examines how antidepressant use in depressed individuals […]
Researchers who previously developed the first 3D human cell culture models of Alzheimer’s disease (AD) that displays two major hallmarks of the condition — the generation of amyloid beta deposits followed by tau tangles — have now used their model to investigate whether the exercise-induced muscle hormone irisin affects amyloid beta pathology. As reported in […]
People who have had a stroke called an intracerebral hemorrhage who take cholesterol-lowering drugs called statins may have a lower risk of having another stroke, especially ischemic stroke, compared to people who also had an intracerebral hemorrhage but were not taking statins, according to a new study. “We looked at whether use of statins after […]
A team of scientists from the University of California, Irvine, believe they have discovered a special antibody which may lead to a treatment for Retinitis Pigmentosa, a condition that causes loss of central vision, as well as night and color vision. The study, Structural basis for the allosteric modulation of rhodopsin by nanobody binding to […]
Groundbreaking research published today in Nature Genetics describes the largest-ever study into the genetics of random “round-the-clock” blood glucose levels. The study, involving almost half a million people of diverse backgrounds, describes new DNA variants influencing blood sugar levels measured “at random.” The team of researchers, led by Professor Inga Prokopenko at the University of […]
Scientists have discovered two new genes that cause head and neck cancer patients to be resistant to chemotherapy, and that silencing either gene can make cancer cells previously unresponsive to chemotherapy subsequently respond to it. The researchers looked through a chemical library, commonly used for drug discovery, and found two substances that could target the […]
PCOS affects 7-10% of women of childbearing age and is the most common cause of infertility. Women are diagnosed with PCOS if they have two of the following criteria: androgen excess (excess male sex hormones such as testosterone), ovulatory dysfunction and polycystic ovaries. “Our study found geographical differences in PCOS in black and white women, […]
Researchers have discovered a new avenue of cell death in Alzheimer’s disease and vascular dementia. A new study, led by scientists at Oregon Health & Science University and published online in the journal Annals of Neurology, reveals for the first time that a form of cell death known as ferroptosis — caused by a buildup […]