Monthly Archives: August 2021

Stem Cell Therapy for Specific Conditions

Stem cell therapy offers hope for rare neurological condition

Posted on by Francisco Fernandez, MD
20
Aug

Pelizaeus-Merzbacher disease (PMD) is a rare, congenital X-linked recessive leukodystrophy caused by a mutation of the proteolipid protein 1 (PLP1) gene (Gencic et al., 1989), resulting in reduced levels of myelination without an inflammatory component or substantial volume loss of brain tissue. PMD is one of a group of hypomyelinating disorders (Helman et al., 2015), […]

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Regenerative Medicine News and General Information

MRI can predict the efficacy of stem cell therapy for Brain injury

Posted on by Francisco Fernandez, MD
19
Aug

Regenerative medicine has yet to designate biomarkers that can identify patients likely to respond to a stem cell therapy based on their expression of a clinical or molecular profile congruent with the therapeutic mechanism-of-action (MOA) of the stem cell for that condition, while withholding treatment from likely non-responders. Ultimately, such patient stratification will be required […]

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Stem Cell Therapy for Specific Conditions

Could stem cell therapy restore smell?

Posted on by Francisco Fernandez, MD
19
Aug

A stem cell therapy delivered into the nose can restore the sense of smell in a mouse model of olfactory loss. The findings were published in May 30 in the journal Stem Cells Reports and provide proof of principle for an approach that has the potential to be of broad utility for a range of […]

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Nutrition and Supplements

Fructose in diet promotes nutrient absorption

Posted on by Francisco Fernandez, MD
19
Aug

Feeding mice high-fructose corn syrup, a widely used sweetener in human diets, has been found to drive an increase in the surface area of the gut that is associated with enhanced absorption of dietary nutrients and weight gain. The incidence of obesity has been steadily increasing, tripling globally between 1975 and 2016, at a high […]

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Nutrition and Supplements

Probiotics for Parkinson’s Disease

Posted on by Francisco Fernandez, MD
18
Aug

Parkinson’s disease (PD) stands in second place after Alzheimer’s disease among common neurodegenerative disorders. An overall incidence rate of 17 per 100,000 persons per year has been reported. The onset of PD is usually at 65 years or older, and it appears slightly more frequently in men than in women. The aging of society around […]

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Anti-Aging

Stem cells in the human skin

Posted on by Francisco Fernandez, MD
18
Aug

The skin is a complicated organ composed of various kinds of cells and has three layers, the epidermis, dermis and subcutaneous adipose tissue. The skin covers the whole body as a barrier and plays important roles in protection from environmental factors including physical and chemical stimuli as well as ultraviolet rays. Recent studies have revealed […]

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Anti-Aging

Stem cells and Aging

Posted on by Francisco Fernandez, MD
17
Aug

Redox and metabolic mechanisms lie at the heart of stem cell survival and regenerative activity. NRF2 is a major transcriptional controller of cellular redox and metabolic homeostasis, which has also been implicated in ageing and lifespan regulation. However, NRF2’s role in stem cells and their functioning with age is only just emerging. The importance of […]

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Platelet-Rich Plasma

Platelet-Rich Plasma for Skin Rejuvenation

Posted on by Francisco Fernandez, MD
17
Aug

Platelet-rich plasma (PRP) is autologous blood plasma with a concentration of platelets well above baseline. The usual concentration of platelets in the blood is approximately 150,000 to 400,000 platelets per cubic microliter. PRP contains 4-7 times the physiologic concentration of platelets. PRP is prepared by centrifugation of blood drawn from the patient before any procedure […]

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Regenerative Medicine News and General Information

Antibiotic Resistance, a Growing Problem

Posted on by Francisco Fernandez, MD
17
Aug

Modern health care is not only reliant on antibiotics to treat infectious disease but also to prevent infections during surgery or immune suppression. Escalating levels of antibiotic resistance impose a substantial burden on medical practice. It is generally believed the evolution of antibiotic resistance is an inevitable consequence of antibiotic use. Antibiotic resistance is the […]

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Nutrition and Supplements

Dietary Supplements and their Interaction with Medications

Posted on by Francisco Fernandez, MD
16
Aug

Nearly 25% of US adults report concurrently taking a prescription medication with a dietary supplement. Some supplements, such as St. John’s wort and goldenseal, are known to cause clinically important drug interactions and should be avoided by most patients receiving any pharmacologic therapy. Some other supplements are predicted to cause interactions based on in vitro […]

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