Monthly Archives: August 2023

New Method to Overcome Antimicrobial Resistance

Antibiotics work by targeting specific parts of a bacteria cell, such as the cell wall or its DNA. Bacteria can become resistant to antibiotics in a number of ways, including by developing efflux pumps — proteins that are located on the surface of the bacteria cell. When an antibiotic enters the cell, the efflux pump […]

Research into Use of Diabetes Medication for Treatment of Metastatic Prostate Cancer

Patients with localised prostate cancer have a good chance of survival, but mortality rates among those with advanced, metastatic forms of the condition remain high.  Until now, the precise mechanism behind the spread of the tumour has not been fully explained. But an international research team headed by MedUni Vienna has succeeded in decoding the […]

Study Shows Promise of Gene Therapy for Alcohol Use Disorder

A form of gene therapy currently used to treat Parkinson’s disease may dramatically reduce alcohol use among chronic heavy drinkers, researchers at Oregon Health & Science University and institutions across the country have found. The study in nonhuman primates showed that implanting a specific type of molecule that induces cell growth effectively resets the brain’s […]

Dissecting What We Know About Wheat Gluten: Could It Play a Part in Brain Inflammation?

In what is believed to be a world first discovery, University of Otago researchers have found wheat gluten causes brain inflammation in mice. “Mice are an excellent model to study human physiology. They have a very similar circulatory, reproductive, digestive, hormonal and nervous system. The study investigated whether a standard diet, referred to as low […]

Possible Biomarker of MS-like Autoimmune Disease Discovered

Multiple sclerosis (MS) is characterized by areas of inflammation in the central nervous system. The immune system attacks the body’s own structures and destroys the covering of nerve cells, known as the myelin sheath. The picture research has painted of the illness is somewhat more complicated, however. It can cause a variety of neurological symptoms, […]

Gut Microbiome Can Increase Risk, Severity of HIV, EBV Disease

Recent research has shown that the bacteria and other microbes in our gut play a supporting role in immunity, metabolism, digestion, and the fight against “bad bacteria” that try to invade our bodies. However, new research published in Nature Biotechnology by Angela Wahl, PhD, Balfour Sartor, MD, J. Victor Garcia, PhD, and UNC School of […]

Parkinson’s Risk and Playing Football

Repetitive head impacts from tackle football can have long-term neurological consequences like chronic traumatic encephalopathy (CTE). But research on the association between participation in tackle football and PD is limited. In the largest study to describe the association between participation in football and the odds for having a reported diagnosis of PD, researchers from the […]

COVID-19 Could Cause Mitochondrial Dysfunction in Heart and Other Organs

A multi-institutional consortium of researchers led by a team at Children’s Hospital of Philadelphia (CHOP) and the COVID-19 International Research Team (COV-IRT) has found that the genes of the mitochondria, the energy producers of our cells, can be negatively impacted by the virus, leading to dysfunction in multiple organs beyond the lungs.  Mitochondria are found […]

Engineered Probiotic Developed to Treat Multiple Sclerosis

Researchers from Brigham and Women’s Hospital  have designed a probiotic to suppress autoimmunity in the brain, which occurs when the immune system attacks the cells of the central nervous system. Autoimmunity in the brain is at the core of several diseases, including multiple sclerosis.  “When a drug is taken, its concentration in the bloodstream peaks […]