In a study led by the University of South Australia (UniSA), a new antibacterial compound known as Narasin was encased in tiny, soft nanoparticles 1000 times smaller than a single strand of human hair and applied in a gel form to targeted acne sites. The drug proved successful against drug-resistant acne bacteria and delivered via […]
Lower back pain affects a sizable portion of the U.S. population, ranging from 1.4% to 20%, and it accounts for substantial health care expenditures. “Our goal was to determine if early PT for patients with lower back pain had an impact on their overall health care resource utilization,” says Richard Skolasky Jr., Sc.D., M.A., the […]
When you are under stress, your brain may release its own cannabinoid molecules to calm you down, activating the same brain receptors as THC derived from cannabis plants. A new Northwestern Medicine study in mice has discovered that a key emotional brain center, the amygdala, releases the body’s own cannabinoid molecules under stress, and these […]
A University at Buffalo-led research team has developed molecules that could help unclog thick, sticky mucus from the lungs of people suffering from cystic fibrosis. The chronic disease is caused by a defective protein channel that prevents chloride ions from leaving cells and creating the watery conditions necessary to clear mucus. Researchers’ synthetic molecules offer […]
Neuromodulation therapies such as transcranial magnetic stimulation, or deep brain stimulation, are emerging as new non-pharmacological treatments for mood disorders. However, understanding which areas of the brain to target to get the best therapeutic effect is still limited. These new findings used brain imaging scans and depression scores from 526 patients who had acquired localized […]
One in three people living with HIV die of TB, which is caused by a bacterium called M. tuberculosis that usually attacks the lungs. It is the world’s second-leading infectious killer after COVID-19. About 1.6 million people die of TB annually, including almost 200,000 people living with HIV, according to the World Health Organization. Bacille […]
The synovium is a membrane-like structure that lines the knee joint and helps to keep the joint happy and healthy, mainly by producing and maintaining synovial fluid. Inflammation of this tissue is implicated in the onset and progression of arthritic diseases such as rheumatoid and osteoarthritis. Therefore, treatments that target the synovium are promising in […]
Currently, more than half a billion people globally are living with diabetes and this number is expected to rise significantly. Chronic diabetic wounds such as foot ulcers (one of the most common and hardest to treat wounds) have therefore become a major global healthcare challenge. Diabetic patients, whose natural wound-healing capabilities are compromised, often develop […]
The liver is the vital organ that orchestrates the overall glucose and fat metabolisms in the human body. Disruption of the fat metabolism in the liver will eventually result in hyperglycemia and hyperlipidemia, which are strong risk factors for developing diabetes, hyperlipidemia, and liver cancer. While the outcomes of fat accumulation in the liver have […]
So-called “triple-negative breast cancer” is a particularly dangerous form of breast cancer. It is characterized by an early relapse and a poor survival rate. Until now, there have only been limited treatment options, and chemotherapy protocols are often not sufficiently effective. Therapy resistance, where cancer cells do not respond to conventional treatments, has long been […]