Heart failure with preserved ejection fraction (HFpEF) is a prevalent form of cardiac decompensation that is increasing with population aging and there still no evidence-based therapies for it. Although is the leading cause of hospitalization in the elderly with almost a third of discharged patients being admitted or dying within 3 months. The search for […]
Peripheral artery disease (also called peripheral arterial disease) is a common condition in which narrowed arteries reduce blood flow to the arms or legs. In peripheral artery disease (PAD), the legs or arms — usually the legs — don’t receive enough blood flow to keep up with demand. This may cause leg pain when walking […]
“Ketogenic” is a term for a low-carb diet (like the Atkins diet). The idea is for you to get more calories from protein and fat and less from carbohydrates. You cut back most on the carbs that are easy to digest, like sugar, soda, pastries, and white bread. When you eat less than 50 grams […]
B vitamins play an important role in different cellular processes that are essential for the nervous system and brain function, including several that help to maintain an appropriate balance between neural inhibition and excitation. It does this by upregulating inhibition and downregulating excitation. This role is important because when the equilibrium shifts towards excitation it […]
Frying oil at high temperatures (approximately 180o C (356ºF) or over) is a widespread processing method used to prepare foods of vegetable and animal origin. Numerous factors influence the stability and performance of frying oil. Edible oils are composed of triacylglycerols (>96%) and endogenous minor components, and at elevated temperatures, oils change significantly due to […]
A good night’s sleep plays an important role in our health and cognitive function, it not only helps maintain good overall health, but it also helps in maintaining our psychological health. As we get older, we can start having alterations in our sleep patterns, which are thought to contribute to cognitive decline and psychiatric disorders […]
Older adults (aged ≥60 years) are the fastest-growing age group in the world and are projected to represent 1 in every 4 adults by 2050. Aging is associated with a progressive loss of muscle mass and strength that manifests as reduced physical activity performance and endurance capacity, imposing a burden on both the individual and […]
Strength training increases muscular strength and hypertrophy, and provides numerous other positive health benefits, including improved functional ability, cardiometabolic risk profile and well-being. A lot of people refrain from performing strength training and other forms of exercise, and as much as a quarter of the world’s population are at risk for developing health-related conditions linked […]
Polycystic ovary syndrome (PCOS) is the most common cause of ovulation disorders, hyperandrogenism, and infertility due to ovulatory dysfunction. It affects more than 7% of chilbearing age women. PCOS is also associated with obesity in 80% of cases and with metabolic syndrome with insulin resistance in 30-40% of cases. The hyperglycemia causes and inhibition of […]
Non-alcoholic fatty liver disease (NAFLD) is characterized by an accumulation of fat in the hepatic parenchymal hepatocytes of more than 5% of the liver weight, without a history of high amounts of alcohol consumption. This condition can cause steatosis and even inflammation, being able to cause necrosis, fibrosis, cirrhosis, and eventually even cancer. It is […]