Author Archives: Gabriel Piña, MD

How Avoid the Progression to T2D in Youth with Prediabetes

The rising prevalence of childhood obesity in US children has led to a parallel rise in the prevalence of prediabetes and overt type 2 diabetes.  Prediabetes is well characterized in adults but less so in children and adolescents: the factors that determine the progression of prediabetes to T2D or its reversion to normoglycemia are poorly […]

COVID Vaccines Safe for Pregnant Women

The COVID-19 pandemic has disproportionately affected pregnant people, who are at higher risk of severe disease compared with similarly aged non-pregnant individuals. Pregnancy leads to an increased risk of hospital admission with COVID-19, because of the severe complications that they presented.  COVID-19 vaccines have been available since December, 2020. Multiple expert groups published positive recommendations […]

Vitamin B12 and Folate May Help Against Fatty Liver Disease

Homocysteine (Hcy) is an important amino acid in your blood that helps create proteins. Hyperhomocysteinemia (HHcy) is a metabolic disorder mainly due to improper removal or accumulation of homocysteine most commonly arising from low dietary intake of Folate (Fol) or Vitamin B12 (B12), those last two vitamin can break down the levels of homocysteine and […]

Elevated Dementia Risk Associated with High Fast Food Intake

There has been a growing body of evidence associating consumption of ultra-processed foods (UPF) with adverse health outcomes including depression, cardiovascular disease, and all-cause mortality.  UPFs are high in sugar, fat, and salt and low in protein and fiber. Some examples are soft drinks, salty and sugary snacks, ice cream, sausage, deep-fried chicken, yogurt, canned […]

Vitamin D May Protect Infants from Atopic Eczema if their Moms Take it During Pregnancy

Atopic eczema is an inflammatory skin disease that can substantially impact affected individuals. It is more common in children, often developing before their first birthday. It’s usually a long-term (chronic) condition, although it can improve significantly, or even clear completely, in some children as they get older. There is increasing evidence that atopic eczema partly […]

Cardiorespiratory Fitness and Mortality Risk

In the last years fitness lifestyle has increased around the world thanks to the diffusion of the media, and obviously for the benefit that it carries. Reaching a healthy weight, glucose control, cardiovascular benefits and emotional regulation are some of the benefits of fitness.  Cardiorespiratory fitness (CRF) emerged as a stronger predictor of all-cause mortality […]

Social Isolation and Loneliness Linked with Cardiovascular and Brain Issues

Social isolation is defined as having infrequent in-person contact with people and loneliness is when a person feels he or she is alone or has less connection with others than desired. More than 4 decades of research have “clearly demonstrated that social isolation and loneliness are both associated with adverse health outcomes. Given the prevalence […]

Stem Cell–Derived Cardiomyocytes Exosomes Promote Myocardial Repair

Induced pluripotent stem cells and their differentiated cardiomyocytes (iCMs) have tremendous potential as patient‐specific therapy for ischemic cardiomyopathy following myocardial infarctions by differentiate into contractile cardiomyocytes (iCMs) and transplanted into the myocardium. Despite initial enthusiasm, the lack of sustained cell engraftment has restricted clinical translation. Exosomes secreted from iCMs (iCM‐Ex) can be robustly collected in […]