Social isolation is defined as having infrequent in-person contact with people and loneliness is when a person feels he or she is alone or has less connection with others than desired. More than 4 decades of research have “clearly demonstrated that social isolation and loneliness are both associated with adverse health outcomes. Given the prevalence […]
Monthly Archives: August 2022
Induced pluripotent stem cells and their differentiated cardiomyocytes (iCMs) have tremendous potential as patient‐specific therapy for ischemic cardiomyopathy following myocardial infarctions by differentiate into contractile cardiomyocytes (iCMs) and transplanted into the myocardium. Despite initial enthusiasm, the lack of sustained cell engraftment has restricted clinical translation. Exosomes secreted from iCMs (iCM‐Ex) can be robustly collected in […]
Pacific whiting is caught in large volumes in the United States but consumers have little familiarity with the mild, white meat fish also known as hake. The gelatin in the skin of Pacific whiting, an abundant fish on the Pacific Coast of North America, may help prevent skin wrinkling caused by ultraviolet radiation, a new […]
Invasive colorectal cancer is a preventable disease. Early detection through widely applied screening programs is the most important factor in the recent decline of colorectal cancer in developed countries. Colorectal cancer remains the third most common cancer and third most common cause of cancer-related mortality in US men and women. [25] In addition, rates of […]
Hypertension is a worldwide problem, and there is some especially prevalence at different groups. Black and Hispanic adults are diagnosed with hypertension at a significantly younger age than are white adults, and they also are more likely than Whites to be unaware of undiagnosed high blood pressure, based on national survey data collected from 2011 […]
Vitiligo is an acquired pigmentary disorder of the skin that is characterized by circumscribed, depigmented macules and patches. The condition is frequently associated with disorders of autoimmune origin, with thyroid abnormalities being the most common. Initial lesions occur most frequently on the hands, forearms, feet, and face, favoring a perioral and periocular distribution. The lesions […]
Osteoarthritis (OA) is a major cause of pain and disability and is detrimental to the quality of life. Many non-invasive treatment options have been recommended to relieve symptoms and extend the quality of life and years of athletic activity for those with OA. Commonly used treatments include non-steroidal anti-inflammatory drugs (NSAIDs), topical agents, and some […]
Low-grade systemic inflammation is associated with an increased risk of various diseases, including cardiovascular disease (CVD) and cancer. Modifiable factors can reduce inflammation and potentially modulate disease risk. One of these factors is dietary fiber intake, in which higher intakes have been associated with lower systemic inflammation in various studies, in both healthy adults and […]
Mesenchymal stem cells (MSCs) therapy is showing potential therapeutic effects on liver function improvement in patients with chronic liver disease and acute chronic liver disease (ACLD). These diseases are mainly caused by alcoholic cirrhosis , high fat blood levels, autoimmune disease or a viral infection, among others. Clinical studies have found that allogeneic BM-MSCs are […]
Gout and pseudogout are the 2 most common crystal-induced arthropathies. Gout is caused by monosodium urate monohydrate crystals; pseudogout is caused by calcium pyrophosphate crystals. There is evidence that gout and heart disease are mechanistically linked by inflammation and patients with gout are at elevated risk for cardiovascular (CV) disease. Risk for myocardial infarction (MI) […]